Dermatologic Care of Patients With Differences of Sex Development

    Sarah Gold, Christina Huang, Rakan Radi, Pranav Gupta, Eric I. Felner, J. Sonya Haw, Krista Childress, Nancy Sokkary, Vin Tangpricha, Michael Goodman, Howa Yeung
    TLDR Dermatologists are crucial in providing personalized care for patients with sex development differences.
    The article reviews the dermatologic care for patients with differences of sex development (DSD), emphasizing the importance of dermatologist involvement in the multidisciplinary care of these patients. It categorizes DSDs into sex chromosome disorders, androgen pathway defects, and gonadal dysgeneses, detailing specific conditions like Klinefelter and Turner syndromes. The review highlights the need for individualized care due to the heterogeneity and complexity of DSDs and underscores the role of hormone replacement therapy in affecting dermatologic conditions. It also stresses the importance of coordinated care and standardized data collection to improve diagnosis and treatment guidelines for DSD-related skin conditions.
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