Clinical Profile and Outcomes of Patients With Systemic Lupus Erythematosus

    September 2024 in “ Cureus ”
    Prasad Chandrakant Bagare, Akshata Borle, Priya Baluni, Gayatri Ekbote, Shashikala Sangale
    This study on systemic lupus erythematosus (SLE) involved 80 patients, predominantly young females, with a mean age of 29.4 years. It highlighted diverse clinical manifestations, with common symptoms including oral ulcers (98.75%) and alopecia (95%). Renal involvement was significant, affecting 50% of patients, and anemia was prevalent in 66.25%. Autoantibody profiles showed high ANA (98.8%) and DsDNA (61.3%) positivity. Over 68% of patients achieved remission, while 16.3% experienced organ damage. The study emphasizes the importance of early detection and targeted management, particularly for renal and mucocutaneous symptoms, and suggests future research on disease progression and treatment strategies.
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