Quality of Life in Patients with Connective Tissue Diseases: Results from the Lupus Extended Autoimmune Phenotype (LEAP) Study

April 2018 in “ Rheumatology ”

John A. Reynolds, Sarah Dyball, Sahena Haque, Hector Chinoy, Ariane L. Herrick, Ellen Bruce, Ben Parker, Ian N Bruce

alopecia lupus anti-Ro antibodies cutaneous SLE rash ulceration hair loss systemic lupus erythematosus

TLDR Many lupus patients experience hair loss, which is linked to anxiety and other skin issues.

The LEAP study found that self-reported alopecia was common in lupus patients, affecting 59.7% of the cohort. Alopecia was most often reported as changes in hair texture and volume across the scalp and was associated with the presence of anti-Ro antibodies. It was not related to age or ethnicity but was linked to other cutaneous SLE manifestations like rash (62.5%) and ulceration (47.5%), indicating a disease-related rather than medication-related cause. Additionally, alopecia was associated with a significant burden of anxiety.

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2 citations, January 2011 in “Elsevier eBooks”

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