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Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Macroalgae compounds offer sustainable, effective benefits for cosmetics.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

JAK inhibitors can effectively reverse hair loss in people with alopecia areata.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

FK506 may stimulate hair growth when applied to the skin.

Methotrexate is not proven effective for inducing remission in ulcerative colitis.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

JAK inhibitors show promise in effectively treating hair loss from alopecia areata.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

Natural ingredients in cosmeceuticals are beneficial for skin and hair health with few side effects.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

New treatments for PCOS are improving fertility and managing symptoms better.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Plant-based products can improve hair and skin health without harmful side effects.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Topical finasteride is an effective and safer treatment for male hair loss.