In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
65 citations
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September 1999 in “The Journal of Dermatology” In this study, complete to excellent hair regrowth was observed in 63.3% of patients with extensive alopecia areata treated with biweekly dexamethasone pulses, although mild side effects were frequent.
49 citations
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December 2018 in “JAAD case reports” This case report describes a patient who developed alopecia after 18 weeks of treatment with dupilumab for atopic dermatitis.
This case study describes a 29-year-old woman diagnosed with both systemic lupus erythematosus and Graves' disease, illustrating a specific combination of autoimmune conditions within Autoimmune Polyendocrine Syndromes.
65 citations
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February 2018 in “The Plant Journal” This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.
18 citations
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January 2010 in “Dermatology Research and Practice” This case report describes a 30-year-old Brazilian male who developed vitiligo lesions following diphencyprone therapy for alopecia areata.
This research found that liposome drug delivery systems, particularly with targeted modifications, show promise for improving effectiveness and reducing toxicity in combination cancer therapies.
1 citations
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June 2019 in “Journal of Cutaneous Immunology and Allergy” This report describes two cases where topical squaric acid dibutylester application in alopecia totalis patients led to severe pustular lesions, necessitating systemic prednisolone treatment.
Psoriasis patients should do moderate exercise like walking or yoga for 30 minutes, 4-5 times a week.
1 citations
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April 2007 in “The FASEB Journal” In this study, D6D knockout mice showed severe deficiency in AA and DHA, leading to unexpected effects on skin health, fertility, and immune cell development.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that skin diseases like atopic dermatitis, acne, and psoriasis are associated with increased odds of alcohol use disorder, with psychiatric conditions such as anxiety and depression partially mediating this relationship, accounting for up to 80% of the risk.
37 citations
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February 2007 in “Experimental Dermatology” This study found that PDCD4 protein expression is reduced in various skin cancers compared to normal skin, suggesting its potential role in preventing or treating certain skin cancers.
34 citations
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February 2016 in “Fertility and Sterility” This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.
November 2024 in “Journal of Investigative Dermatology” Polygenic Score can help predict severe psoriasis and psoriatic arthritis.
16 citations
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January 2000 in “Journal of dermatological treatment” This study found that calcipotriol scalp solution was more effective than a coal tar-based shampoo for treating mild to moderate scalp psoriasis and showed continued efficacy with long-term use.
22 citations
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August 2011 in “Journal of the American Academy of Dermatology” This article highlights that erosive pustular dermatosis of the scalp is often under-diagnosed in the United States, potentially leading to unnecessary surgery.
41 citations
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November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
September 2019 in “Journal of Investigative Dermatology” This study found that patients with vitiligo report the highest willingness-to-pay for disease control and cure compared to those with other chronic skin conditions, suggesting DLQI may not fully capture treatment priorities.
3 citations
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October 2020 in “Arthritis Care & Research” This review discusses the advancement and validation of outcome measures for pediatric systemic lupus erythematosus to improve disease monitoring and treatment precision but reports no new clinical findings.
34 citations
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July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
In this study, researchers observed that atopic dermatitis may alter the appearance of allergic patch test reactions, demonstrating specific patterns like perifollicular erythema and yellowish areas that could aid in interpreting patch tests using dermoscopy, particularly in ambiguous cases.
April 2018 in “Journal of Investigative Dermatology” This study found that psoriasis patients value medication providing substantial clearance of symptoms at an average of $34,208/year, significantly below the annual cost of biologic treatments.
33 citations
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August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
39 citations
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March 2008 in “British Journal of Dermatology” This study documented the onset of lichen planopilaris during treatment with etanercept.
6 citations
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January 2020 in “Open Journal of Psychiatry” This study concludes that the Greek version of the Dysmorphic Concern Questionnaire is a reliable and valid tool for assessing body dysmorphic disorder-related concerns in both research and clinical settings.
21 citations
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January 2015 in “Dermatologic Therapy” This letter discusses a case of erosive pustular dermatosis of the scalp linked to topical latanoprost use for androgenetic alopecia, but reports no clinical results.
2 citations
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September 2018 in “Journal of Separation Science” This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
1 citations
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August 2019 In this study, researchers developed a pemphigus mouse model expressing anti-Desmocollin 3 antibodies and found it mimicked atypical pemphigus with distinct pathological features compared to the standard Desmoglein 3 model.
1 citations
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January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
January 2014 in “Journal of Central South University(Science and Technology)” This study found that poly(propylene carbonate maleate) microspheres can successfully prolong finasteride release over 42 days, showing potential for long-term sustained drug delivery.