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Vitamin D receptor is crucial for starting hair growth after birth.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

K16 can partially replace K14 but causes hair loss and skin issues.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Some alternative treatments for hair loss might work, but more research is needed.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Meis1 is crucial for skin health and tumor development.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Rac1 is essential for proper hair structure and color.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Lack of cystatin M/E causes thin hair and dry skin.

Only skin melanocytes, not other types, can color hair in mice.