iNOS Inhibits Hair Regeneration in Obese Diabetic (ob/ob) Mice

    May 2018 in “ Biochemical and Biophysical Research Communications ”
    Mari Sasaki, Shohei Shinozaki, Hitoshi Morinaga … Kentaro Shimokado
    Studysummary In this study, researchers found that inhibiting inducible nitric oxide synthase (iNOS) promoted hair growth in diabetic mice, suggesting iNOS-derived nitric oxide contributes to hair loss under diabetic inflammatory conditions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 13

    1. Alopecia and the Metabolic Syndrome Clinics in Dermatology · 2017
    2. Hair Follicle Characteristics as Early Marker of Type 2 Diabetes Medical Hypotheses · 2016
    3. Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone Biochemical and Biophysical Research Communications · 2016
    4. Canonical and Non-Canonical Wnt Signaling Control the Regeneration of Amputated Rodent Vibrissae Follicles Journal of Molecular Histology · 2016
    5. Metabolic Syndrome in Androgenic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016
    6. Telogen Elongation in the Hair Cycle of ob/ob Mice Bioscience, Biotechnology, and Biochemistry · 2015
    7. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014
    8. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    9. Leptin Controls Hair Follicle Cycling Experimental Dermatology · 2014
    10. Hair Cycle Control by Leptin as a New Anagen Inducer Experimental Dermatology · 2013
    11. HSL Attenuates Follicular Oxidative Stress and Enhances Hair Growth in ob/ob Mice Plastic and Reconstructive Surgery – Global Open · 2013
    12. Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum Australasian Journal of Dermatology · 2013
    13. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001