3 citations
,
June 2021 in “PLOS ONE” This study found that topical application of the BRAF inhibitor vemurafenib improved wound healing and promoted hair follicle regeneration in a diabetic murine model.
1 citations
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November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
1 citations
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January 2022 in “Stem cell biology and regenerative medicine” This review describes various in vitro and ex vivo hair follicle models used to study hair growth and regeneration and explores their potential for developing hair loss treatments, but it does not report new results.
June 2026 in “Journal of Investigative Dermatology” This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.
April 2026 in “Molecules” This study suggests that extracellular vesicles derived from Saccharomyces cerevisiae may enhance hair follicle-related cellular processes, highlighting their potential for biomedical and cosmetic applications.
February 2026 in “Preprints.org” In this study, extracellular vesicles from Saccharomyces cerevisiae demonstrated multifunctional bioactivity, enhancing cell proliferation and migration, reducing inflammation, and promoting collagen gene expression in hair follicle–related cells.
December 2023 in “International journal of molecular sciences” This in vitro study found sex chromosome differences affect steroidogenic enzyme activity and androgen receptor expression in human skeletal muscle cells, showing varied responses to testosterone exposure between 46XY and 46XX cells.
July 2023 in “Journal of Clinical Medicine” In this study, researchers investigated factors predicting resistance to clomiphene citrate in women with anovulatory PCOS, identifying AMH and SHBG levels as significant indicators, but they found no reliable thresholds for predicting resistance to the standard 50 mg/day dose.
119 citations
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October 2011 in “Journal of Veterinary Internal Medicine” This review discusses the clinical manifestations and immune response to Rhodococcus equi infection in foals but reports no new clinical results.
18 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.
11 citations
,
November 2011 in “Neuroreport” In this study, paroxetine's antihyperalgesic effect in a rat model of neuropathic pain was shown to be mediated by increased levels of the neurosteroid allopregnanolone in the spine.
9 citations
,
July 2007 in “Journal of Investigative Dermatology” This study found that exposure to 12-O-tetradecanoyl-phorbol-13-acetate in mouse skin caused changes in claudin expression and localization, indicating disruption and eventual recovery of the epidermal barrier.
2 citations
,
September 2022 in “Frontiers in Nutrition” This study found no significant difference in the persistence of new symptoms or quality of life improvements with 200,000 IU of vitamin D3 compared to placebo in patients post-COVID-19 hospitalization.
May 2025 in “The Journal of Rheumatology” This case report suggests that a proactive physical therapy model can be effective for improving physical function and meeting exercise guidelines in patients newly diagnosed with systemic lupus erythematosus.
January 2025 in “Biomedicines” In this study, female rats given high doses of testosterone showed decreased endometrial thickness and lower mRNA levels of components in the LIF signalling pathway, indicating that excessive testosterone may negatively impact endometrial receptivity and potentially affect fertility.
January 2025 in “The Journal of Dermatology” This study found that patients with severe alopecia areata are willing to accept increased risks of serious infection, cancer, and blood clots when opting for a higher dose of ritlecitinib, valuing the potential for greater hair regrowth efficacy compared to a lower dose.
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.
September 2017 in “Journal of Investigative Dermatology” In this study, low-dose 453 nm blue light appeared to enhance hair growth by interacting with specific photoreceptors in the outer root sheath cells.
20 citations
,
August 2020 in “Scientific Reports” In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.
110 citations
,
August 2015 in “Neuropsychopharmacology” In this study, high-dose dutasteride significantly reduced several core symptoms of PMDD compared to placebo, supporting the role of neurosteroids in this condition.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
92 citations
,
December 2012 in “Current opinion in genetics & development” This review covers the recent advances in understanding how Turing models may explain various morphogenetic processes, but it reports no new experimental findings.
58 citations
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September 2019 in “EMBO Molecular Medicine” This study found that the CDK4/6 inhibitor palbociclib may protect human hair follicles from the damaging effects of taxane chemotherapy by inducing G1 arrest in stem/progenitor cells.
53 citations
,
November 2021 in “Molecular Human Reproduction” This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.
46 citations
,
September 2023 in “Cell Reports” This study reports that sebaceous glands can regenerate after injury through stem cell plasticity, with hair-follicle-derived stem cells replacing sebaceous gland progenitors and playing a crucial role in the regeneration process, which is dependent on FGFR2 signaling and aided by hair growth induction.
41 citations
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September 2005 in “Wound Repair and Regeneration” This study found that hydrogen peroxide interfered with scarless healing in a murine fetal wound repair model, potentially by inducing transforming growth factor-beta1, which may contribute to increased fibrosis.
30 citations
,
February 2022 in “Stem Cell Reviews and Reports” This review of stem cell-based tissue engineering treatments in preclinical burn wound models reports promising improvements in skin repair, suggesting potential as an enhanced therapy for burn wounds.
27 citations
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March 2019 in “PLoS ONE” This study suggests that Thyroxine (T4) may promote key features of human skin wound healing, such as re-epithelialization and angiogenesis, in an ex vivo model.
17 citations
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November 2017 in “PLoS ONE” This study observed dynamic behaviors such as cluster formation, migration, and active proliferation of transplanted bone marrow cells in a mouse model, providing insight into cellular-level changes post-transplantation.
9 citations
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January 2022 in “Reproductive Biology and Endocrinology” This study aimed to identify reliable predictors for the effectiveness of metformin therapy in weight loss and reduction of plasma androgen levels in PCOS women, highlighting the unpredictability of response to treatment.