The Prostaglandin Synthases, COX-2 and L-PGDS, Mediate Prostate Hyperplasia Induced by Low-Dose Bisphenol A

    August 2020 in “ Scientific Reports ”
    Shuangshuang Wu, Dongyan Huang, Xin Su … Zuyue Sun
    Studysummary In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.
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    Research cited in this study 5

    1. Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women Journal of The European Academy of Dermatology and Venereology · 2019
    2. Association Between Male Pattern Baldness and Prostate Disease: A Meta-Analysis Urologic Oncology: Seminars and Original Investigations · 2017
    3. Multi-Therapies in Androgenetic Alopecia: Review and Clinical Experiences Dermatologic Therapy · 2016
    4. In Silico Prediction of Prostaglandin D2 Synthase Inhibitors from Herbal Constituents for the Treatment of Hair Loss Journal of Ethnopharmacology · 2015
    5. Oral Administration of Low-Dose Bisphenol A Promotes Proliferation of Ventral Prostate and Upregulates Prostaglandin D2 Synthase Expression in Adult Rats Toxicology and Industrial Health · 2015