78 citations,
June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
46 citations,
September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
15 citations,
January 2019 in “Experimental Dermatology” Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
May 2015 in “Journal of The American Academy of Dermatology” A heart transplant patient developed a skin condition called epidermodysplasia verruciformis after taking immune-suppressing drugs.
146 citations,
July 2018 in “Regenerative Medicine” Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
47 citations,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
2 citations,
July 2020 in “Electromagnetic Biology and Medicine” Low-frequency electromagnetic fields help regenerate hair follicles using a mix of skin cells.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
33 citations,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
30 citations,
May 1999 in “Food and chemical toxicology” Procyanidin B-2 is safe to use on skin as a hair growth product.
29 citations,
November 2014 in “Experimental Dermatology” Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.
24 citations,
April 2005 in “The Journal of Dermatology” Putting ketoconazole on the skin can help mice grow hair.
23 citations,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
17 citations,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
6 citations,
January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
1 citations,
November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
396 citations,
May 2011 in “Cell stem cell” Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
330 citations,
December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
101 citations,
July 2020 in “Dermatologic therapy” COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.
66 citations,
July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
65 citations,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
23 citations,
July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
19 citations,
September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
19 citations,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
7 citations,
August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
6 citations,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
4 citations,
February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.