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In this study, the researchers used molecular docking to identify Erythrabyssin II from Erythrina subumbrans as a potential candidate for anti-alopecia treatment, comparable to minoxidil, suggesting clinical trials are needed to evaluate its pharmacological effects.

This molecular docking study reported that danoprevir, remdesivir, and saridegib exhibit stronger binding affinities to the main protease of SARS-CoV-2 than the control, suggesting their potential as inhibitors of the virus's replication process.

This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.

In this study, researchers using network pharmacology and molecular docking methods found that compounds from Avicennia Marina could inhibit hepatitis C virus infection by targeting key proteins such as AKT1 and TNF-α, showing potential for anti-HCV treatments.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.

This study found that 62 plasma proteins are significantly associated with the risk of obstructive sleep apnea, offering potential targets for new therapeutic strategies.

In this study, different drying methods for Hedychium spicatum rhizomes significantly affected the essential oil yield, antioxidant potential, and compound composition, with the HSOV30 method yielding the highest oil content, antioxidant activity, and specific compound levels such as 1,8-cineole and elemol.

This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.

In this study, researchers found that the evolutionary and structural features of the oFGF5 gene in sheep may influence hair follicle development and hair growth regulation.

This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.

This study analyzed watercress oil and confirmed its phytochemical profile, UV absorption properties, and potential efficacy for hair growth, supporting traditional hot oil applications.

This study highlights the role of abnormal DNA methylation in skin disorders such as atopic dermatitis and psoriasis, suggesting these epigenetic changes may serve as biomarkers and targets for potential treatments.

This study identified ten novel compounds that may effectively target steroid 5 alpha-reductase 2 (5αR-2) for potential treatment of benign prostate hyperplasia, exhibiting comparable binding energies to existing drugs like finasteride and dutasteride.

This study identified 1965 different metabolites in various tissues of *Oresitrophe rupifraga* Bunge using a targeted metabolomics approach and found significant metabolic differences between its aboveground and underground parts, providing insights into the plant's unique growth traits and potential cultivation and utilization.

This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.

This study explored the potential of stigmasterol as a treatment for androgenetic alopecia through various simulation techniques, finding promising interactions with key genes involved in hair loss, but further experimental validation is needed before clinical application.

This study found that isorhamnetin, a compound from the Rampai plant, showed a lower affinity energy in molecular docking tests compared to Minoxidil, indicating potential as an androgen receptor antagonist for alopecia therapy in silico, with favorable pharmacokinetic characteristics in ADME-Tox predictions.

This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.

This study used molecular docking to analyze nine compounds from the Siddha herbal formulation Kushtakudori ennai, finding that they may effectively interact with androgen receptors to hinder hair follicle shrinkage and potentially reduce hair loss, showing potential as anti-alopecia treatments.

In this bibliometric study, researchers analyzed 96 publications from 2000 to 2022 to identify trends in HIV-1 capsid inhibitor research, highlighting the USA as a leading contributor and emphasizing the importance of molecular studies and drug discovery in advancing antiretroviral therapy.

This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.

This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.

This study suggests that Hejie Shengfa Decoction may help treat alopecia areata by influencing immune and inflammatory pathways, regulating apoptosis, and enhancing the follicular microenvironment.

This research highlights the potential of personalized medicine and advanced therapeutic strategies, including 3D biomaterials and natural products, to enhance wound healing and skin care, while also acknowledging the limitations and safety concerns associated with these innovations.

This study identified natural compounds from Iris plants that showed potential as inhibitors of urease and carbonic anhydrase-II enzymes, suggesting their possible use in treating related disorders.

This study found that the peptides RMYYY and VMYMI displayed stronger binding energy and more frequent interactions with HPGDS compared to the native inhibitor, suggesting potential as future therapeutic drugs.

This study evaluated the anti-alopecia activity of compounds from Merremia peltata leaf in rabbits and found that scopolin has a promising effect on hair growth and androgen receptor affinity, potentially offering a new treatment option for alopecia.

In this study, researchers identified three proteins, DEFB1, HGFAC, and CYB5D2, as potential drug targets for alopecia areata, and suggested that the traditional Chinese medicine ingredient cimigenol shows promise in interacting with DEFB1 for potential treatment.

This study developed an organic hair conditioner using chitosan-thiadiazole conjugates that showed improved hair detangling, moisture retention, and protection without causing irritation, promising an environmentally sustainable approach to hair care.