Bibliometric Analysis and Visualization of Research Trends on HIV-1 Capsid Inhibitors (2000–2022)
October 2023
in “
Frontiers in Pharmacology
”
TLDR Research on HIV-1 capsid inhibitors has progressed significantly, with the U.S. leading in contributions.
The study provides a bibliometric analysis of research trends on HIV-1 capsid inhibitors from 2000 to 2022, identifying an increase in publications, especially from 2019 to 2022. The United States leads in productivity and collaboration, with significant contributions from China and England. The Journal of Virology is the most prolific journal, and Drexel University and Vanderbilt University are top institutions. Simon Cocklin is the most productive author, while Christopher Aiken has the highest citation impact. The research focus has shifted from microstructural analysis to developing capsid inhibitors, with GS-6207 noted as a promising long-acting antiviral drug. The study underscores the role of molecular biology and computer-aided drug design in advancing capsid inhibitor discovery, indicating progress towards more effective anti-HIV treatments and potential future breakthroughs.
