2 citations
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August 2020 in “Clinical, Cosmetic and Investigational Dermatology” This study found that a combination of oral compounds improved metabolic activity, cell viability, and proliferation in hair follicular keratinocytes, with L-cystine playing a key role in protection against oxidative stress.
2 citations
,
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes a family where a TP63 mutation was linked with prominent alopecia and mild ectodermal dysplasia features.
2 citations
,
June 2017 in “Journal of biomedicine and translational research” In this study, Oligonol® was shown to regulate gene expression related to cell proliferation and inflammation in human dermal papilla cells.
2 citations
,
June 2017 in “Pediatric Dermatology” This case report describes a 2-year-old boy in critical condition who developed anagen effluvium, possibly due to hypotension and hypoxia triggering hair follicle apoptosis.
2 citations
,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses recent advancements in skin epigenetics, focusing on how epigenetic mechanisms regulate gene expression during normal skin function and their dysregulation in conditions like skin disorders and cancer, but reports no new clinical results.
2 citations
,
January 2015 in “Elsevier eBooks” This review discusses current research on epigenetic changes in autoimmune skin diseases like vitiligo and alopecia areata, noting that the field is still developing and lacks extensive analysis.
2 citations
,
January 2013 This review discusses various forensic applications of hair analysis, such as species identification and drug addiction testing, and reports no new study results.
2 citations
,
June 1994 in “Der Hautarzt” This article discusses the challenges in evaluating drug effects on hair growth and emphasizes DNA-flowcytometry as a reliable method for this purpose, without reporting new clinical results.
1 citations
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December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.
1 citations
,
November 2024 in “Orphanet Journal of Rare Diseases” Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.
1 citations
,
March 2024 in “International journal of molecular sciences” This review discusses how ionizing radiation causes skin damage by inducing cellular senescence in keratinocytes, which secrete inflammatory mediators, recruiting immune cells and exacerbating inflammation, impacting the skin barrier function and healing.
1 citations
,
August 2023 in “Journal of cutaneous pathology” This case report describes an 8 cm giant pilomatricoma on a 67-year-old man's scalp, revealing distinct transcriptional patterns related to hair follicle factors and keratin through spatial gene expression analysis.
1 citations
,
January 2023 in “Life sciences” This study demonstrated that elevated GABA levels can worsen stress-induced hair growth inhibition in mice, while GABAA antagonists like ginkgolide A may help alleviate these effects.
1 citations
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November 2022 in “Journal of Investigative Dermatology” This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
1 citations
,
March 2022 in “IntechOpen eBooks” This article reviews the functions and locations of skin stem cells and their role in regeneration and differentiation, relating age-associated skin changes to decreased stem cell functionality; it reports no new experimental findings.
1 citations
,
February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study uses cryo-electron microscopy to reveal how androgen receptor forms a non-obligate dimer to bind DNA, with implications for prostate cancer development.
1 citations
,
July 2021 in “IntechOpen eBooks” This review discusses unspecific factors involved in the pathogenesis of skin diseases and potential ways cytokeratin changes might alleviate these conditions, but reports no new clinical results.
1 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibroblast loss in the upper dermis from UVR exposure is linked to a deregulated inflammatory response, with T cells playing a protective role in fibroblast survival.
1 citations
,
September 2020 in “Leonardo” This exhibition explored the intersection of art and biotechnology, encouraging discussions on genetics and societal roles through provocative contemporary art installations.
1 citations
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January 2020 in “Recent Research in Genetics and Genomics/Recent Research in Genetics and Genomics ” In this study, high doses of Lepidium sativum seeds extract were reported to cause toxicity and tissue damage in animals, suggesting the need for careful use under medical supervision.
1 citations
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September 2019 in “Journal of Investigative Dermatology” In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.
1 citations
,
November 2017 in “Expert opinion on orphan drugs” This review discusses the genetic basis of ectodermal dysplasia, highlighting that identification of gene pathologies enhances diagnosis and supports prenatal DNA testing, but it reports no new clinical results.
1 citations
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September 2016 in “Journal of Dermatological Science” This study found that FGF18 signaling helps protect hair follicles from radiation damage by maintaining the resting phase and supporting stem cell survival, potentially reducing radiation-induced hair loss.
1 citations
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August 2016 in “Hanbang an'i'bi'in'hu pibu'gwa haghoeji” In this study using lab models, YangHyulEum Gami-Bang (YHEG) was associated with promoting hair growth and inhibiting factors that contribute to hair loss.
1 citations
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April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
1 citations
,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses various topics from the 62nd Annual Montagna Symposium on the Biology of Skin, focusing on the diverse effects of light on skin biology, and reports no new clinical results.
1 citations
,
July 2011 in “Hair transplant forum international” This article reports increased DNA methylation of the androgen receptor gene in the occipital hair follicles of men with androgenetic alopecia but presents no clinical results.
1 citations
,
April 2009 in “Wiley Encyclopedia of Forensic Science” This article reviews the rationale and science behind forensic hair examinations and discusses the role of microscopic and DNA techniques in differentiating hair sources but reports no new findings.
1 citations
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May 2001 in “Pharmacology & Toxicology” This review discusses the preclinical findings on cyproterone acetate and suggests that while it has a low potential cancer risk for patients, its tumor effects in female rats may involve both genotoxic and mitogenic mechanisms.
1 citations
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January 1999 in “Proceedings of the British Society of Animal Science” This research investigates apoptosis and bcl 2 expression in hair follicles cultured with and without biotin, but it reports no new results.