1 citations
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May 2024 in “Cureus” This case series describes five patients with rare facial lichen planopilaris, detailing the clinical presentation and treatment of their pigmentary changes and scarring alopecia.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
4 citations
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March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
October 2024 in “Journal of Pakistan Association of Dermatologists” In this cross-sectional study, both follicular lichen planus and discoid lupus erythematosus were identified as common causes of scarring alopecia, affecting young people with a more favorable prognosis for hair regrowth in discoid lupus erythematosus compared to follicular lichen planus.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” This review discusses the formation of gintonin LPAs in ginseng during processing and reports no new clinical results; the authors suggest potential benefits against degenerative diseases through LPA receptors.
November 2024 in “Cureus” The authors reported a case of significant scalp edema accompanying lichen planopilaris in a middle-aged woman, suggesting a potential new variant of edematous scalp conditions as a reaction to scarring alopecia.
February 2025 in “Vestnik dermatologii i venerologii” This case report describes a 47-year-old patient with scarred alopecia diagnosed as discoid lupus erythematosus, where treatment with multiple medications led to clinical improvement.
1 citations
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November 2024 in “Cutis” PLLA injections can cause hair loss and skin issues.
September 2022 in “Journal of the American Academy of Dermatology” This study compares the prevalence of vitamin D deficiency in patients with lichen planopilaris/frontal fibrosing alopecia to the general US population, highlighting an area not well-explored in existing research.
105 citations
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December 2009 in “Archives of dermatology” This overview discusses primary cicatricial alopecias, focusing on lichen planopilaris, and highlights the challenges in treatment and the progressive nature of hair loss despite symptom management, without providing new clinical results.
15 citations
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September 2014 in “Dermatologic surgery” This study found that diode laser reduced axillary hair more effectively but with greater pain than intense pulsed light, with both methods producing lasting and safe results.
September 2025 in “Clinical Case Reports” In this study, researchers suggested that adipose-derived exosomes could be a promising treatment option for lichen planopilaris, particularly in cases resistant to standard therapies, by potentially aiding in symptom management and hair preservation.
5 citations
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August 2001 in “International Journal of Dermatology” This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.
July 2024 in “Skin Appendage Disorders” This review discusses the role of trichoscopy in diagnosing lichen planopilaris and reports no clinical results; the authors emphasize early recognition to potentially prevent permanent scarring.
October 2013 in “CRC Press eBooks” This review outlines current and potential cosmetic and dermatological applications of low-level light therapy, like photorejuvenation and hair regrowth, and reports no new clinical findings.
August 1978 in “Archives of Dermatology” This case report details a rare instance of granulomatosis disciformis chronica et progressiva affecting both skin and lymph node tissue in a 31-year-old man.
20 citations
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January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This review discusses lysophosphatidic acid's role in neuropathic pain and cholestatic itch, highlighting its complex signaling pathways, but reports no new clinical results.
8 citations
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October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
24 citations
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November 2023 in “International Journal of Molecular Sciences” This review highlights that platelet-rich plasma and adipose-derived stem cell therapy may offer safe and promising improvements for managing symptoms of genital lichen sclerosus, with a potential synergistic benefit when combined.
October 2017 in “Doctoral thesis, UCL (University College London).” This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.
7 citations
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August 2020 in “Animal biotechnology” This study found that lncRNA-599547 positively regulates the expression of the Wnt10b gene by interacting with miR-15b-5p, enhancing the inductive property of dermal papilla cells in cashmere goats.
291 citations
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January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
June 2001 in “Proceedings of SPIE” The authors concluded that low energy laser therapy may serve as a useful complementary treatment for skin diseases such as lichen planus, infectious finger pulpits, scalp alopecia, and crural ulcers.
50 citations
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February 2004 in “Genomics” This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
April 2024 in “African Journal of Biological Sciences” This case report describes a patient with systemic lupus erythematosus who developed Degos disease and non-scarring alopecia, highlighting dermoscopy's role in diagnosis and treatment prognosis.
102 citations
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August 2008 in “Genes & Development” This study found that laminin-511 is crucial for hair morphogenesis in mice, as it influences primary cilia formation and dermal papilla maintenance through noggin and sonic hedgehog signaling.
June 2023 in “International Journal of Dermatology” This study reviewed 41 cases of lichen planus pigmentosus in patients from southeastern Tunisia, highlighting its prevalence among older individuals and notable differences compared to patterns observed in an Indian cohort.
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.
26 citations
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September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.