June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
92 citations,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
91 citations,
December 2006 in “Proceedings of the National Academy of Sciences” Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
51 citations,
April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
10 citations,
May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
8 citations,
July 2014 in “Hair transplant forum international” Bio-enhanced hair restoration, using methods like growth factors, stem cells, and ATP, results in better hair growth and density than traditional hair transplants.
7 citations,
March 2022 in “The FASEB journal” Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
4 citations,
November 2021 in “Pharmaceuticals” Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.
3 citations,
August 2018 in “Stem cells international” Hair follicle cells help maintain and support stem cells and blood cell formation.
130 citations,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
July 2024 in “Skin Research and Technology” The products significantly promote hair growth and maintain hair bulb health.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
April 2018 in “Journal of Investigative Dermatology” A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
5 citations,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
September 2017 in “Journal of Investigative Dermatology” The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.
September 2017 in “Journal of Investigative Dermatology” Hair follicle cells change their DNA packaging during growth cycles and when grown in the lab.
September 2017 in “Journal of Investigative Dermatology” Blue light helps hair growth by affecting specific proteins in hair follicle cells.
April 2017 in “Plastic and reconstructive surgery. Global open” Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.
August 2014 in “Journal of The American Academy of Dermatology” Obesity is linked to more severe hair loss in adult men and to excess hair growth, but its effects on hair conditions are complex and need more research.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
21 citations,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
11 citations,
September 1996 in “Neuroscience letters” Adding fetal calf serum helps Merkel cells survive and change shape.
10 citations,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
5 citations,
September 2003 in “Archives of Facial Plastic Surgery” Follicular-unit grafting is an effective hair transplant method that looks natural and has a high success rate.
3 citations,
October 2017 in “Journal of Cosmetic Dermatology” Dr. Muhammad Ahmad created a hair classification system to help improve hair restoration surgery outcomes.
2 citations,
July 2021 in “Biochemical and Biophysical Research Communications” CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.