Hair Follicle Associated Pluripotent Stem Cells Stimulate Hair Growth in Transplanted Mice

    December 2022 in “ Scientific Reports ”
    Koya Obara, Jose Reynoso, Yuko Hamada, Yusuke Aoki, Yutaro Kubota, Noriyuki Masaki, Yasuyuki Amoh, Robert M. Hoffman
    Image of study
    TLDR Stem cells from whiskers can be transplanted to stimulate hair growth.
    The study demonstrated that Hair follicle associated pluripotent (HAP) stem cells, taken from the upper parts of whisker follicles in mice, can stimulate hair growth when transplanted into the skin of athymic nu/nu nude mice, which are unable to produce mature hair shafts due to a mutation in the FOXN1 gene. The transplanted HAP stem cells migrated to the resident hair follicles of the recipient mice, promoting hair growth. The transplanted mice showed significant increases in hair-growth area, hair length, and hair-density score compared to non-transplanted control mice. The study suggests that HAP stem cells could potentially be used in cell therapy for hair growth stimulation, but also noted that repeated transplantation may be necessary to maintain hair growth. The number of mice used in the experiment was not mentioned.
    Discuss this study in the Community →

    Research cited in this study

    12 / 12 results

    Related Community Posts Join

    6 / 1000+ results

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  138 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community 22 yr asian male 2 year fin results

      in Progress Pictures  135 upvotes 1 year ago
      The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

      community Please explain this Minoxidil phenomena

      in Minoxidil  60 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  330 upvotes 9 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

    Related Research

    3 / 3 results