![Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase](/images/research/d91300a7-4d66-4d2c-90ac-293b0dbc5ff5/small/21048.jpg)
research Synthesis of Spiro[cyclohexane-1,2'-[2H]indene] Derivatives as Inhibitors of Steroid 5α-Reductase
Compound 15a was effective in inhibiting 5α-reductase.
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research Acne and Its Management
Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Synergistic Effect of Rice Bran Extract and Extremely Low-Frequency Electromagnetic Fields on Dermal Papilla/Melanocytes in Melanogenesis
Rice bran extract and low-frequency electromagnetic fields together may help treat vitiligo and white hair.
research Effect of Topically Applied Minoxidil on the Survival of Rat Dorsal Skin Flap
Minoxidil applied before and after surgery improves skin flap survival in rats.
research Leprosy on the Scalp: A Case Report
A man from Brazil had a rare case of leprosy on his scalp, which improved with treatment.
research Integrin α3β1 in Hair Bulge Stem Cells Modulates CCN2 Expression and Promotes Skin Tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research Alopecias: Practical Evaluation and Management
The document provides a practical guide for diagnosing and treating various types of hair loss.
research Management of Advanced Hair Loss Patterns
Use a frontal forelock pattern to manage advanced hair loss.
research Committing to a Hairy Fate: Epigenetic Regulation of Hair Follicle Stem Cells
Epigenetic changes are crucial for hair follicle stem cells to function properly.
research Dealing With Misleading Advertising in the Face of Declining Government Resources
The document concludes that with limited resources, the government should focus on impactful enforcement against misleading advertising and encourage businesses to follow guidelines to prevent deception.
research Trichodynia Revisited
Trichodynia is a painful scalp condition not directly linked to the amount or type of hair loss and may involve psychological factors, with treatments showing mixed results.
research A Population-Based Study of the Risk of Osteoporosis and Fracture with Dutasteride and Finasteride
Dutasteride and finasteride have similar risk for osteoporosis and fractures in older men.
research Nasal Sporotrichosis in Children
Three children with nasal fungal infections were successfully treated with potassium iodide and sometimes itraconazole.
research A Keratin Fiber Sheath
Hair fibers may have a unique, non-protein sheath not previously identified.
research Management of Complications Associated with Upper Facial Rejuvenation
Careful planning and technique in upper facial rejuvenation can minimize risks like hair loss, nerve damage, and scarring.
research Impact of Hormones on Female Sexual Function and Dysfunction
Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.
research Does a Picture of the Human Placenta Predict the Future?
The shape and size of the placenta may help predict future health risks for both mother and child.
research Permanent Localized Hair Repigmentation Following Herpes Zoster Infection
Herpes zoster infection can cause permanent hair color change in the affected area.
research The Genetically Programmed Hair Growth Cycle And Alopecia: What Is There To Know?
The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
research Discriminating in Favor of or Against Men with Increased Risk of Finasteride-Related Side Effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research Beyond Ethnicity in Dermatology
The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.
research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Interpolated Melolabial Flaps: Reconstruction of Alar and Columellar Units
Using cheek skin and cartilage grafts for nose reconstruction after skin cancer surgery can maintain shape and function but may require multiple surgeries and hair removal in men.
research Thermodynamic Modeling of the Gas-Antisolvent Process for Precipitation of Finasteride
The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.
research Spatial Gene Profiling in the Ischemic Heart
A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
research Neonatal Occipito-Linear and Temporo-Fronto-Parietal Alopecia: Can Non-Marginal and Marginal Forms of Transient Neonatal Hair Loss Be Found Together?
A baby boy had two types of temporary hair loss at birth, which might be two forms of newborn hair loss combined.
research Advances in Therapeutic Management of Complicated Demodicosis in Canines
Effective treatment with antiparasitic, antibacterial, anti-inflammatory, and antiallergic medications can lead to recovery in dogs with complicated demodicosis.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma
VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.