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Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Different types of skin cells play specific roles in development, healing, and cancer.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.