58 citations,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
20 citations,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
14 citations,
July 2021 in “Reviews in endocrine and metabolic disorders” SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
5 citations,
February 2013 in “Dermatology and therapy” Crescina® lotion helps reduce hair loss and increase hair growth in males with androgenetic alopecia.
May 2024 in “Scientific Reports” Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
34 citations,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
23 citations,
December 2004 in “Differentiation” Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
10 citations,
February 2010 in “Acta Histochemica Et Cytochemica” c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
24 citations,
May 2010 in “Hautarzt” Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.
53 citations,
May 1986 in “Clinics in endocrinology and metabolism” Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.
49 citations,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
18 citations,
September 2018 in “Experimental physiology” Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
16 citations,
January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
14 citations,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
370 citations,
September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
25 citations,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
20 citations,
January 2018 in “Expert Opinion on Drug Safety” Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
19 citations,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
13 citations,
July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
11 citations,
May 2002 in “The Journal of Urology” Finasteride doesn't harm bone density in older men with BPH.
6 citations,
April 2017 in “Frontiers in Pharmacology” Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
4 citations,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
4 citations,
October 2022 in “American journal of physiology. Heart and circulatory physiology” Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
3 citations,
January 2008 in “Endocrine journal” A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
2 citations,
January 2013 in “Elsevier eBooks” The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
1 citations,
May 2023 in “Cell reports medicine” Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
June 2022 in “Journal of Experimental Biology and Agricultural Sciences” Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.