July 2024 in “Biological and Pharmaceutical Bulletin” This study found that 18-β-Glycyrrhetinic acid, a licorice component, stimulated human hair follicle cell proliferation, inhibited testosterone 5α-reductase, and suppressed TGF-β1, suggesting potential for treating androgenetic alopecia by promoting hair growth and prolonging the anagen phase.
53 citations
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July 2002 in “Journal of Investigative Dermatology” The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.
8 citations
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January 2016 in “Annals of Dermatology” This study found that the ALAVAX complex, containing 5-ALA and GHK peptide, may increase hair count in male pattern hair loss patients over 6 months without adverse events.
February 2021 in “Dermatologic Therapy” This study concluded that intralesional lyophilized growth factor injections are safe and improve trichoscopic hair parameters and clinical scores in patients with female pattern hair loss.
August 2023 in “European journal of dermatology/EJD. European journal of dermatology” This study reported that therapeutic make-up significantly improves the long-term quality of life for patients with facial dermatoses, showing a sustained benefit one year after application, particularly in younger patients.
26 citations
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April 2011 in “British Journal of Dermatology” This study identified novel mutations in the DSG4 gene in a Japanese patient with monilethrix, affecting protein interactions that may disrupt hair shaft structure.
This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.
April 2024 in “African Journal of Biological Sciences” In this case report, a 38-year-old woman with Degos disease and non-scarring alopecia experienced significant hair regrowth with the current treatment protocol, highlighting its potential effectiveness in such complex conditions.
2 citations
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January 2022 in “Experimental Dermatology” This paper proposes that GDNF signaling may enhance skin regeneration and hair follicle formation by influencing dermal fibroblast differentiation, particularly following injury.
6 citations
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February 2024 in “JAAD International” ChatGPT is preferred for creating dermatology patient handouts, but all models can be useful with oversight.
February 2024 in “Heliyon” In this study, AGA patients exhibited distinct lipidomic profiles and higher metabolic syndrome prevalence compared to controls, with certain lipids correlated to key AGA-related factors like DHT, PGD2, and TGF-β1.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
40 citations
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March 1982 in “British Journal of Dermatology” This study found that women experiencing diffuse hair loss had significantly lower levels of plasma sex-hormone binding globulin compared to controls, while their testosterone levels remained normal.
April 2019 in “Journal of Investigative Dermatology” This study suggests that dietary grape powder may reduce the severity of atopic dermatitis in a mouse model, highlighting its potential in both prevention and intervention settings.
1 citations
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September 2025 in “Dermatology and Therapy” This review suggests that glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have potential benefits for dermatologic conditions but may also cause adverse skin reactions and impact surgical outcomes.
April 2022 in “International Journal of Health Sciences (IJHS)” This study found that combining low-level light therapy with platelet-rich plasma significantly improved hair parameters in men with androgenic alopecia, although most improvements decreased after treatment stopped.
30 citations
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October 2010 in “Biochemical and biophysical research communications” This study found that the Gsdma3 gene is necessary for normal hair follicle differentiation in mice, with its mutation leading to progressive hair loss and defects in hair structure.
82 citations
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July 2012 in “Brain pathology” This study found that LGR5 may play a significant role in maintaining brain cancer stem-like cells and is associated with glioma progression and poor outcomes.
June 2026 in “Frontiers in Oncology” In this study, researchers found that deficiencies in Gsdma1/2/3 significantly inhibited the initiation and progression of cutaneous squamous cell carcinoma (cSCC) in mice, suggesting GSDMA's role in promoting cSCC proliferation and its potential as a therapeutic target.
November 2025 in “Journal of Investigative Dermatology” BTNL2 helps protect hair follicles from immune attacks.
November 2023 in “Scientific Reports” In this study, researchers used NIH hairless mice to uncover genetic markers associated with hair loss and identified a Lama3 point mutation as a potential genetic contributor, creating a mutant mouse model that may advance the study of androgenetic alopecia.
6 citations
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January 2015 in “Journal of clinical & experimental dermatology research” This study suggests that combining monoammonium glycyrrhizinate/glycine/DL-methionine tablets with 5% carpronium chloride may reduce alopecia areata area more effectively than carpronium chloride alone, particularly in patients with allergic factors.
July 2020 in “Journal of Tissue Engineering and Reconstructive Surgery” April 2024 in “Dermatology The American Medical Journal” This study developed expert consensus guidelines on the safe and effective prescription of low-dose oral minoxidil for treating hair loss by engaging 43 dermatologists from 12 countries in a structured Delphi process, yielding 78 consensus items on safety, efficacy, dosing, and monitoring.
January 2026 in “Forum Dermatologicum” This study reviewed cases of Graham–Little-Piccardi–Lassueur syndrome and found that topical treatments were generally ineffective, while systemic therapies like prednisone, hydroxychloroquine, and isotretinoin led to partial hair regrowth and disease stabilization, highlighting the importance of early diagnosis and systemic therapy to improve outcomes.
86 citations
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January 2020 in “British Journal of Dermatology” This study developed the Alopecia Areata Investigator Global Assessment (AA-IGA) to measure scalp-hair loss in alopecia areata patients, incorporating perspectives of both patients and clinicians to define treatment success.
October 2025 in “Dermatologica Sinica” This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.
5 citations
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January 2021 in “Veterinary dermatology” This study found that adding low-level laser therapy to conventional treatment for canine acral lick dermatitis significantly increased hair growth compared to conventional therapy alone, but did not significantly reduce licking behavior.
2 citations
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September 2017 Laser Lax is a new tool that measures scalp looseness accurately and comfortably.