August 2026 in “Genetics and Molecular Research” This study found that hydroalcoholic extracts of Trigonella foenum-graecum L. seeds were rich in bioactive phytochemicals and demonstrated potential therapeutic properties against dandruff, alopecia, and oxidative stress through molecular docking analysis of key constituents such as diosgenin, kaempferol, and quercetin.
This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.
27 citations
,
February 2017 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a topical formulation with compounds from the monoterpenoid family significantly improved hair growth indicators like anagen:telogen ratio, hair fall, and visual hair density in men and women with pattern hair loss.
86 citations
,
August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
2 citations
,
March 2014 in “European Journal of Chemistry” This study developed and validated a liquid chromatography-mass spectrometry method for accurately identifying and quantifying tamsulosin and finasteride in pharmaceutical forms, showing its effectiveness for quality control.
77 citations
,
April 1999 in “Dermatologic Clinics” This article reviews how new observations have revolutionized surgical hair restoration and highlights the logical applications and prior illogical judgments that delayed this advancement, without reporting new results.
6 citations
,
January 2010 in “Actas Dermo-Sifiliográficas” This review covers the current procedure for follicular unit hair transplantation, noting that recent advancements have made the results natural and undetectable, but it presents no new experimental findings.
1 citations
,
June 2023 in “Journal of applied crystallography” This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.
March 2012 in “Society for Endocrinology BES 2012” This study presents a novel assay that allows for the simultaneous measurement of various androgens and 5α-reductase inhibitors in male serum, facilitating research into the biochemical effects of these inhibitors.
1 citations
,
January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
July 2003 in “Hair transplant forum international” This article mentions that the slot correction technique by Dr. Patrick Frechet has been a valuable tool in the author's 100% hair restoration surgery practice but does not provide new clinical results.
7 citations
,
July 1995 in “PubMed” Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
April 2017 in “Journal of Investigative Dermatology” This study identified the dermal sheath as a key component of the hair follicle niche, essential for outer root sheath regression during the hair cycle, highlighting its importance in hair follicle support and regulation.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed distinct cellular and transcriptomic differences among various subtypes of cutaneous T-cell lymphoma, particularly highlighting characteristics unique to folliculotropic mycosis fungoides.
August 2018 in “Journal of Investigative Dermatology” This study of alopecia areata patients found that a 10 mg twice-daily dose of oral tofacitinib led to significant hair regrowth, suggesting it may be beneficial for treatment.
2 citations
,
December 2019 in “Journal of Dermatological Treatment” This study found that metabolic syndrome negatively affected the response to intradermal dutasteride injection in female pattern hair loss, with participants showing reduced terminal hair and increased vellus hair compared to those without the syndrome.
136 citations
,
September 2019 in “Journal of Clinical Investigation” This study found that mature dermal adipocytes have high plasticity, undergoing dedifferentiation and redifferentiation, which plays a significant role in hair cycling and wound healing.
December 2020 in “Journal of Skin and Sexually Transmitted Diseases” This study found no significant correlation between serum testosterone or DHEAS levels and the severity of acne or FPHL in a localized female population, but noted most patients had low testosterone levels.
1 citations
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February 2018 in “Plastic and Aesthetic Research” This article describes a new instrument, the KD spreader, designed to help novice physicians perform follicular unit extraction hair transplantation with reduced trauma and operator fatigue, but it does not report new clinical results.
December 2024 in “Dermatology”
1 citations
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December 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, TrichoScan characteristics, particularly hair density and terminal hair percentage in the midscalp, were found to predictively classify female pattern hair loss in a Chinese population.
3 citations
,
June 2020 in “Dermatologic Surgery” This study found that dense-packing megasession follicular unit extraction is a safe and effective method for treating extensive scarring alopecia, with a graft survival rate of 85% and high patient satisfaction.
27 citations
,
November 2008 in “Facial Plastic Surgery” This article outlines the technical aspects, benefits, and challenges of follicular unit extraction for hair transplantation, but it reports no new clinical findings.
7 citations
,
June 2000 in “Journal of the American Academy of Dermatology” This study found that betamethasone valerate in a foam vehicle has comparable total coverage to traditional topical corticosteroid vehicles, despite less coverage per unit of foam.
8 citations
,
July 1990 in “Archives of Dermatology” This case report details a fixed-drug eruption in a woman linked to the use of dextromethorphan, marking it as a previously unreported skin reaction to this medication.
2 citations
,
January 1980 in “Archives of Dermatology” This letter discusses concerns about the term "telogen effluvium" and suggests using "telogen defluxion" instead, but reports no new results.
1 citations
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January 2020 in “Skin appendage disorders” Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
64 citations
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June 2009 in “Journal of The American Academy of Dermatology” This article discusses frontal fibrosing alopecia, noting potential connections to lichen planopilaris, but reports no new clinical findings.
1 citations
,
April 2023 in “Langmuir” This study used molecular dynamics simulations to model the outer surface of human hair, illustrating complex behavior and potential adsorption interactions with fatty acids, which may inform cosmetic formulation development.
6 citations
,
October 2016 in “Journal of Cellular Physiology” This study found that human dermal fibroblasts can promote the viability and proliferation of microvascular endothelial cells in vitro, revealing important interactions at play in hair growth.