28 citations
,
December 2019 in “Skin appendage disorders” This review discusses medication-induced gray hair repigmentation, highlighting that certain anti-inflammatory drugs and melanogenesis stimulators can cause diffuse repigmentation, though evidence remains low-quality and these medications are not currently indicated for this purpose.
28 citations
,
September 2013 in “Expert Opinion on Therapeutic Patents” This review discusses various resveratrol derivative patents for therapeutic, nutraceutical, and cosmetic use, but reports no clinical results and notes that claims of improved efficacy lack trial evidence.
28 citations
,
May 2012 in “Veterinary Dermatology” In this study, dogs with hair cycle disorders, especially those with alopecia X, showed a significant increase in the number of kenogen follicles, suggesting impaired induction of new hair growth phases.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
27 citations
,
December 2013 in “Endocrinology” This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.
27 citations
,
March 2019 in “PLoS ONE” This study suggests that Thyroxine (T4) may promote key features of human skin wound healing, such as re-epithelialization and angiogenesis, in an ex vivo model.
26 citations
,
June 2012 in “The Journal of Obstetrics and Gynecology of India” This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.
26 citations
,
August 2019 in “Stem Cell Research & Therapy” This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.
26 citations
,
October 2016 in “Clinics in Dermatology” This article discusses various hormonal therapies for acne and provides practical treatment guidelines for managing hormonally related acne, but it reports no new research findings.
26 citations
,
March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” This review discusses the definition, causes, diagnostic strategies, and treatment options for hirsutism in women without reporting new clinical results, and highlights the impact of the condition on self-esteem.
26 citations
,
May 2012 in “Cellular and Molecular Life Sciences” This review discusses the structure, expression, regulation, and potential roles of NcoA4 in cancer and other pathologies, reporting no new experimental findings.
26 citations
,
February 2011 in “Anais Brasileiros De Dermatologia” This review discusses the pathophysiology, diagnosis, and treatment of polycystic ovary syndrome, emphasizing the critical importance of early diagnosis and treatment to prevent metabolic complications and improve quality of life.
26 citations
,
March 2009 in “Dermato-endocrinology” This review discusses the evaluation, clinical presentation, and cutaneous manifestations of congenital adrenal hyperplasia, focusing on differential diagnosis challenges with polycystic ovary syndrome, and reports no new clinical findings.
26 citations
,
October 2007 in “Experimental Dermatology” This study found that l-carnitine stimulated hair growth in vitro by promoting proliferation and reducing apoptosis in human scalp hair follicles, suggesting potential as a treatment for hair loss.
26 citations
,
April 2007 in “Journal of pediatric gastroenterology and nutrition” This case report describes an adolescent girl with polycystic ovarian syndrome and endogenously elevated androgen levels who developed a hepatic adenoma, suggesting a link between the two conditions.
25 citations
,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.
25 citations
,
January 2022 in “Endocrine journal” This study suggests that hormonal changes may contribute to the persistent symptoms of long COVID, with specific patterns observed in serum hormone levels related to fatigue and sensory dysfunction.
25 citations
,
June 2019 in “Endocrine Related Cancer” This review discusses the structure and function of steroid nuclear receptors, particularly focusing on androgen receptor dysregulation in prostate cancer and androgen insensitivity syndromes, without reporting new experimental results.
25 citations
,
June 2013 in “Obesity Reviews” This review examines mesotherapy for local fat reduction, detailing its mechanisms, safety concerns, and the need for research toward FDA-approved uses, but reports no new clinical findings.
25 citations
,
March 2012 in “Journal of oncology pharmacy practice” This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.
24 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
24 citations
,
November 2016 in “Molecular Medicine Reports” This study found that women with acne resistant to conventional treatments had significantly higher levels of testosterone, DHEA‑S, prolactin, and LH, suggesting potential underlying hormonal disorders.
24 citations
,
February 2015 in “Experimental Cell Research” This study found that overexpression of the transcription factor NFIC may enhance the proliferation and differentiation of stem cells from the apical papilla, suggesting its potential role in dentin/root regeneration.
24 citations
,
November 2013 in “Trends in pharmacological sciences” This article describes a potential novel approach to reduce chemotherapy-induced hair loss by enhancing the expression of specific transporters in hair follicles, but reports no clinical results.
24 citations
,
July 2013 in “Oncologist” This study suggests that the combination of bendamustine and rituximab is at least as effective and possibly offers a better therapeutic index than other standard regimens as first-line treatment for certain lymphoma patients.
24 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.
24 citations
,
January 2010 in “Annales d'endocrinologie” This review discusses treatment options for hirsutism in women of childbearing age, focusing on the use of contraceptives, CPA, spironolactone, and third-line therapies, and reports no clinical results.
24 citations
,
January 2003 in “Journal of Investigative Dermatology” In this study, a synthetic antagonist of the p75 neurotrophin receptor was found to significantly inhibit hair follicle regression in murine skin cultures, suggesting a potential role in treating hair disorders characterized by premature catagen entry.
24 citations
,
September 2001 in “Journal of Dermatological Science” This study found that cyclophosphamide-induced hair follicle damage in C3H mice could be remodelled into intact anagen hair follicles with topical cyclosporin A, especially in anagen IV stage follicles.
24 citations
,
January 2001 in “Dermatologic clinics” This article reviews the use of hormonal therapies in dermatology, specifically focusing on their pathophysiologic rationale, indications, commonly used drugs, and pretreatment evaluations, and it reports no new research findings.