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Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Fungi-produced compounds can change plant root growth.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.