January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
August 2001 in “Journal of Cutaneous Medicine and Surgery” Prednisone has risks for lupus patients, isotretinoin is safe for mental health, transplant patients risk skin cancer, and various treatments are effective for specific skin conditions.
August 2023 in “Dermatology and Therapy” This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.
December 2020 in “Forum Dermatologicum” In this case report, a combination treatment of intralesional triamcinolone acetonide, oral acitretin, and topical clobetasol propionate showed effectiveness in reducing symptoms of Graham-Little-Piccardi-Lasseur syndrome in one patient over two months, with no new areas of hair loss observed.
2 citations
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January 2012 in “Hair therapy & transplantation” This study observed that DDAIP-HCl enhanced the permeation of minoxidil through human cadaver skin, suggesting potential for improved treatment efficacy in male pattern hair loss.
July 2025 in “Pakistan Journal of Intensive Care Medicine” In this randomized controlled trial, researchers observed that topical clobetasol propionate 0.05% was significantly more effective than topical tacrolimus 0.1% for treating alopecia areata, with a higher treatment success rate of 74.2% versus 45.2%, suggesting clobetasol as a preferred first-line topical therapy.
August 2025 in “Annals of Medicine” This study found that mycophenolate mofetil can enhance skin pigmentation in vitiligo models by activating the WNT signaling pathway and increasing melanin-related gene expression.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” This study investigated the efficacy and safety of a gel combining topical calcipotriol and steroid for alopecia areata. It found the combination worked similarly to steroids alone in reducing hair loss, but with fewer side effects.
January 2010 in “Annals of King Edward Medical University” This study concluded that combination therapy with 5% minoxidil and 0.05% betamethasone dipropionate cream was more effective for hair regrowth in alopecia areata than 5% minoxidil alone.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This randomized controlled trial found that intralesional vitamin D3 was as effective and safe as intralesional triamcinolone acetonide for treating patchy alopecia areata on the scalp, with no significant influence from serum vitamin D levels on treatment response.
1 citations
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January 2011 in “MOspace Institutional Repository (University of Missouri)” This study reports that topical immunotherapy with SADBE and DPCP is the most effective short-term treatment for hair regrowth in children with severe alopecia areata compared to other treatments.
September 1987 in “International Journal of Dermatology” This article is a reply to Dr. Greenwald and does not provide new clinical results.
1 citations
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March 2006 in “Journal of Cosmetic Dermatology” This case report describes a 79-year-old woman whose skin lesions were attributed to a cosmetic product, with complete resolution following mechanical removal of material and metronidazole treatment.
24 citations
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March 2009 in “Archives of dermatological research” This study found that a combination therapy of oral corticosteroid and oral PUVA led to scalp hair regrowth in patients with intractable alopecia totalis and universalis within two months.
13 citations
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November 2005 in “Epilepsia” This study suggests that the anticonvulsant effects of deoxycorticosterone in young rats may be mediated by its metabolites and interactions with multiple receptors, including mineralocorticoid and progesterone receptors.
20 citations
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December 2006 in “Archives of dermatology”
3 citations
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August 2022 in “JAAD case reports” This review discusses the emerging evidence for low-dose oral minoxidil in treating various types of alopecia, without providing new clinical results.
4 citations
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September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
January 2016 in “Indian Journal of Paediatric Dermatology” This study found that a combination treatment using oral and topical steroids with topical minoxidil was well-tolerated in children with severe recalcitrant alopecia areata, showing good responses except in alopecia universalis cases.
1 citations
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March 2019 in “Journal of Interdisciplinary Medicine” This case report details a middle-aged man with multiple sclerosis who developed difficult-to-evaluate skin reactions after daclizumab treatment, noting only slight improvement with additional therapies.
23 citations
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March 2019 in “Environmental Chemistry Letters” This review examines the role of cyclodextrins in improving the solubility, stability, and bioavailability of steroid drugs but does not report new experimental findings.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that melatonin may reduce the dose of prednisone needed for treating alopecia areata and its associated side effects by attenuating free radical damage on the immune system.
18 citations
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December 2015 in “PubMed” This study found that intralesional triamcinolone was more effective than topical betamethasone for hair regrowth in patients with localized alopecia areata.
30 citations
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July 2007 in “PubMed” This study found that oral mini-pulse therapy with betamethasone was safe and effective for treating extensive alopecia areata in a majority of patients.
June 2017 in “Journal of the American Academy of Dermatology” The new cream is safe and effective for mild to moderate atopic dermatitis.
3 citations
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June 2020 in “Journal of Dermatological Treatment” In this study, researchers found that triamcinolone acetonide provided earlier visual improvement in alopecia areata treatment, but by 12 weeks, both triamcinolone acetonide and betamethasone 1.75 mg/ml showed similar effectiveness compared to lower-dose betamethasone and placebo.
2 citations
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January 2009 in “Journal of Drug Delivery Science and Technology” This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.
August 2025 in “Indian Dermatology Online Journal” In this study, both methotrexate gel and betamethasone lotion were found to be effective and safe treatments for localized alopecia areata, with similar overall response rates. However, methotrexate gel had a higher incidence of local side effects, such as irritant dermatitis and itching.
33 citations
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May 1984 in “Journal of Pharmacy and Pharmacology” This study found that while systemic absorption of DHT from liposomes was negligible, the topical biological effect was weaker compared to DHT dissolved in acetone on the female hamster flank organ model.
2 citations
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November 2007 in “Journal of Investigative Dermatology” This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.