The Hair Loss Encyclopedia

Childhood Alopecia Areata: What Treatment Works Best?

January 2011 in “ MOspace Institutional Repository (University of Missouri) ”

James Haynes, Robert K. Persons, Barbara Jamieson

alopecia areata topical immunotherapy squaric acid dibutylester diphenylcyclopropenone intralesional steroids topical corticosteroids oral corticosteroids topical cyclosporine photodynamic therapy topical minoxidil AA SADBE DPCP

TLDR Topical immunotherapy with SADBE and DPCP is most effective for short-term hair regrowth in children with severe alopecia areata.

The document reviewed treatments for childhood alopecia areata (AA) and found that topical immunotherapy using squaric acid dibutylester (SADBE) and diphenylcyclopropenone (DPCP) induced the most significant short-term hair regrowth in children with severe AA, based on 4 small individual cohort studies and 1 moderately sized retrospective case review. Intralesional steroids were effective in inducing hair regrowth greater than 50% in children with limited AA, according to 1 retrospective cohort study. However, other treatments such as topical and oral corticosteroids, topical cyclosporine, photodynamic therapy, and topical minoxidil showed no benefit over placebo, as evidenced by 14 randomized controlled trials and 3 within-patient studies.

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Research cited in this study

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Interventions for Alopecia Areata

research Interventions for Alopecia Areata

164 citations , April 2008 in “Cochrane library”

Current treatments for alopecia show no significant long-term benefits.

research Alopecia Areata in Children: Response to Treatment with Diphencyprone

84 citations , August 1991 in “British Journal of Dermatology”

Most children treated with diphencyprone regrew some or all of their hair.

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community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 64 upvotes 5 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community Onion Juice - An effective topical treatment for Alopecia Areata 🧬

in Treatment 2 years ago

Onion juice, when applied topically, is an effective treatment for Alopecia Areata, showing significant hair regrowth in both males and females. The study suggests it could be interesting to test its effectiveness on Androgenic Alopecia.

community 5 months and a half in topical minoxidil 5% everynight, 3 months of multivitamins + zinc (conzace), and almost 2 weeks or 2 weeks of triamcinolone (to determine if alopecia areata) 17M

in Is this regrowth? 9 upvotes 11 months ago

The user has been using topical minoxidil 5% for five and a half months, multivitamins with zinc for three months, and triamcinolone for almost two weeks to address hair loss. They are considering starting finasteride at age 18 and are unsure about hair regrowth progress.

community mbp alopecia areata or vitamin deficiency

in Chat 1 year ago

A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

community What are the odds baricitinib will get a topical otc version for androgenic alopecia?

in Research/Science 2 years ago

Baricitinib, approved for alopecia areata, might be considered for treating receding hairlines. The discussion is about the possibility of an over-the-counter topical version for androgenic alopecia.

community Why are there no studies on Topical Vitamin D3 for AGA?

in Research/Science 10 upvotes 1 year ago

Topical Vitamin D3 may stimulate hair growth and has been used for Alopecia Areata. There is a question about the lack of research on its use for Androgenetic Alopecia (AGA).

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