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TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Oxidative stress contributes to hair graying and loss as we age.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.