August 2016 in “Anaplastology” This study reports that controlled release PRP therapy using dalteparin and protamine micro-particles may be effective for hair growth and skin rejuvenation in women.
February 2025 in “Drug Delivery and Translational Research”
3 citations
,
May 2019 in “Journal of Cosmetic Dermatology” This study found that a 12-week supplementation with MePL, a solution of miliacin encapsulated within polar lipids, significantly reduced hair density in the telogen phase and improved scalp dryness and hair brightness in women with telogen effluvium.
April 2026 in “International Journal of Allied Medical Sciences and Clinical Research” In this study, researchers formulated an herbal hair serum with plant extracts like Hibiscus and Nigella and observed that it demonstrated acceptable physical properties and potential anti-dandruff activity, proposing it as a safe and effective alternative to synthetic hair care products.
3 citations
,
August 2021 in “The Open Dermatology Journal” This study found that the formulated herbal hair serum improved hair growth and hair weight with minor sensitivity after application and demonstrated stability for seven days.
January 2026 in “JPRAS Open” In this pilot study, PDLLA scalp microinjections showed improvement in physician-rated Global Aesthetic Improvement Scale scores over 12-24 weeks for 90% of patients with non-scarring alopecia, with no serious adverse events reported, although findings remain preliminary due to methodological limitations.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal hair serum, finding it effective against certain fungi and bacteria and showing potential for hair regrowth comparable to standard treatments, suggesting it may serve as a natural alternative for promoting hair health.
April 2023 in “Journal of Investigative Dermatology” This study found that patients receiving PRP treatments for various types of alopecia and skin rejuvenation had a higher risk of adverse events and lower self-assessment scores when injections were administered at shallower depths, with significant correlations between patient and physician assessments across different indications.
4 citations
,
September 2024 in “PubMed” This review discusses the efficacy and safety of platelet-rich plasma for facial rejuvenation but reports no definitive clinical results, noting the evidence remains insufficient for firm conclusions.
1 citations
,
September 2019 This review discusses platelet-rich plasma and microneedling as potential regenerative therapies for hair loss disorders but reports no new clinical results; the authors suggest using these approaches alongside existing treatments.
2 citations
,
June 2021 in “Cosmoderma” This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.
May 2025 in “Journal of research in pharmaceutical science.” In this study, researchers developed and tested a herbal hair serum using hibiscus, flaxseed, and aloe vera, finding that the optimal formulation effectively reduces frizz, enhances hair smoothness and glossiness, and provides moisturizing benefits without harmful ingredients compared to conventional hair serums.
February 2026 in “Trends in Sciences” In a testosterone-induced mouse model, this study found that exosomes from injectable Platelet-Rich Fibrin (i-PRF) significantly reduced inflammation, oxidative stress, and apoptosis, while enhancing hair regeneration, with the greatest improvements seen when combined with minoxidil, suggesting potential as a novel treatment for androgenetic alopecia.
January 2024 in “Dermatology Review” This study found that combining platelet-rich plasma with 4% hydroquinone was more effective in reducing melasma symptoms than using hydroquinone alone.
January 2024 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
1 citations
,
March 2017 in “Journal of evolution of medical and dental sciences” This study compared microneedling combined with platelet-rich plasma and microneedling with minoxidil for treating androgenetic alopecia in men, finding both approaches effectively improved hair density and alopecia grade.
39 citations
,
August 2022 in “Cell Death and Disease” This study found that a dopamine-methacrylated hyaluronic acid hydrogel enhances the efficacy of adipose-derived stem cells in promoting skin regeneration, potentially involving the Notch signaling pathway.
In this study, researchers developed a herbal hair serum using Alkanna tinctoria root extract and other natural ingredients, demonstrating promising results in promoting hair growth, enhancing manageability, and minimizing side effects, making it a safe and effective alternative to chemical hair products.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a herbal hair serum made from natural ingredients, including fenugreek, flaxseed, and Murraya koenigii extracts, was evaluated for its physicochemical properties and safety, showing promising stability, low irritation potential, and effective antioxidant activity as an eco-friendly alternative to chemical hair care products.
December 2024 in “Biochemical and Biophysical Research Communications” LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.
April 2023 in “Journal of Investigative Dermatology” This review discusses randomized trials on PRP and laser therapy for vitiligo, acne scars, and skin rejuvenation, finding combination therapy may yield clinical improvements but calls for more diverse studies.
December 2023 in “Deleted Journal” This research project focused on developing a herbal hair serum using natural ingredients like Flaxseed, Aloe Vera, and Vitamin E, aimed at addressing issues like hair fall and dandruff while promoting overall hair health. Results of the study are not reported.
January 2025 in “Annals of dental specialty” This study found that Aloe Vera, injectable platelet-rich fibrin (i-PRF), and their combination affected the proliferation of mesenchymal stem cells derived from human hair follicles, with varying concentrations tested for proliferation and cytotoxic effects.
1 citations
,
January 2021 in “PubMed” In this study, PRP combined with microneedling was found to be an effective treatment for patients with androgenetic alopecia who did not respond to minoxidil and finasteride, with the majority of participants experiencing very good results after a minimum of four sessions.
December 2025 in “Aesthetic Cosmetology and Medicine” This study reported that platelet-rich fibrin (iPRF) therapy may improve scalp health and hair appearance in women, showing beneficial changes in scalp hydration, redness, oiliness, and hair density, thickness, and loss.
2 citations
,
March 2020 in “Plastic and Reconstructive Surgery” This review discusses platelet-rich plasma and microneedling in aesthetic medicine, providing a comprehensive literature summary and practical insights, but reports no new clinical results.
June 2023 in “QJM: An International Journal of Medicine” This study found that combining fractional CO2 laser treatment with platelet-rich plasma led to a statistically significant improvement in hair regrowth for male androgenetic alopecia, compared to using the laser treatment alone.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
January 2025 in “International Journal of Pharmacognosy and Clinical Research” This study reported the development of a scalp serum containing Beta-Sitosterol and nutrient-rich oils, showing stable physicochemical properties, suggesting potential for promoting hair growth and scalp health, though further clinical testing in humans is needed to confirm effectiveness.
13 citations
,
February 2020 in “Journal of the American Academy of Dermatology” This study found that both oral tranexamic acid and microneedling improve melasma treatment outcomes when added to standard therapy, with microneedling showing a more sustained remission.