July 2023 in “Fayoum University Medical Journal” This study evaluated minoxidil at different concentrations and found it effective in treating androgenetic alopecia when used with Dermapen injectors, noting mild adverse effects that patients tolerated well, and recommended dermoscopy for early diagnosis and treatment monitoring.
42 citations
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January 2021 in “Journal of Clinical Medicine” This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.
30 citations
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November 2024 in “ACS Materials Au” This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.
July 2024 in “Periodontology 2000” This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.
32 citations
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June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
19 citations
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October 2020 in “Biomedical Microdevices” This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.
3 citations
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October 2021 in “Dermatologic Therapy” This study demonstrated that PRP treatment improved hair metrics in androgenetic alopecia, with the dermapen method proving more effective than the point-by-point technique for specific hair growth indicators.
December 2023 in “Jurnal Penelitian Pendidikan IPA” In this laboratory study on mice, researchers found that both platelet-rich plasma and salmon DNA serum promoted wound healing, with platelet-rich plasma providing faster results due to its bioactive growth factors.
December 2023 in “International Journal of Health and Pharmaceutical” This study investigated the effects of a derma pen treatment using green betel leaf extract cream on hair development in female Wistar rats, highlighting the antioxidant and anti-inflammatory properties of betel leaves that may aid in hair growth and condition.
3 citations
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March 2024 in “arXiv (Cornell University)” This study describes an AI-powered system for diagnosing dermatological conditions, achieving a weighted score of 0.87 in both contextual understanding and diagnostic accuracy, suggesting it could enhance tele-dermatology applications by supporting remote consultations and care access in underserved regions.
May 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviewed literature on using the dermapem technique for treating female androgenetic alopecia and found that it effectively controls and stabilizes hair loss by enhancing nutrient supply and absorption in the scalp, with the technique considered safe.
September 2022 in “Dermatologic Therapy” This article is a correspondence that discusses platelet-rich plasma application methods for androgenic alopecia but reports no new clinical results.
131 citations
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May 2015 in “Experimental Dermatology” This review explores the development and cosmeceutical applications of microneedles for skin treatment, without reporting new clinical results, emphasizing safety and public perception as key factors for commercialization.
36 citations
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December 2016 in “Dermatologic Therapy” In this study, TCA peel was found to be the most effective treatment for stable non-segmental vitiligo among the modalities tested, and it increased both MMP-9 and IL-17 tissue levels.
This source reviews advancements in microneedle-based cosmeceutical delivery, discussing new technologies and highlighting a burgeoning area of research involving microneedling combined with stem cell delivery for anti-aging, without finding measurable changes in skin barrier function or appearance during the study period.
October 2022 in “Dermatologic Therapy” This study found no significant difference in the overall effectiveness of fractional CO2 laser plus triamcinolone acetonide versus microneedling plus the same treatment for resistant alopecia areata, though initial hair regrowth appeared more frequently in the laser group.
1 citations
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January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that combining platelet-rich plasma with microneedling and subcision was effective in treating atrophic acne scars in over 80% of patients with minimal adverse effects.
5 citations
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August 2019 in “Journal of The American Academy of Dermatology” This paper reviews the use of microneedling alone and in combination with platelet-rich plasma for various skin conditions, but it reports no new clinical findings.
1 citations
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September 2019 in “Hair transplant forum international” This article introduces a needleless microjet injector using laser pulse energy for tattoo pigments in scalp micropigmentation, highlighting an almost painless procedure without anesthesia.
July 2026 in “Lasers in Medical Science” In this study, the Peninsula Timerevert Needle was found to provide effective treatment for skin photoaging and acne scars with less pain and shorter treatment duration compared to EndyMed, although it caused more bleeding.
5 citations
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January 2023 in “Journal of Cosmetic Dermatology” This study found that microbotox, especially when injected intradermally, effectively reduces enlarged facial pores with higher patient satisfaction and longer-lasting results compared to its topical application after microneedling.
November 2025 in “Dermatology Reports” This review found that microinfusion of medications using tattoo devices (MMP®) shows potential as a minimally invasive method for treating ailments like alopecia and basal cell carcinoma, offering notable improvements with minimal side effects due to localized drug delivery.
July 2020 in “CRS 2020 Virtual Annual Meeting” This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.
3 citations
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February 2020 in “International Journal of Research in Dermatology” According to this source, dermaroller therapy is increasingly used in dermatology for conditions like acne scars and melasma due to its cost-effectiveness, minimal adverse effects, and ability to enhance topical treatment absorption, making it a popular resurfacing option across all skin types.
May 2016 in “Hair transplant forum international”
January 2024 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
16 citations
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July 2000 in “Dermatologic surgery” This paper contains author contact information and disclosures without reporting new research findings or results.
17 citations
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September 2022 in “Biomaterials Research” This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.
4 citations
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April 2024 in “Cellular and Molecular Biology” In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.
January 2023 in “Skin appendage disorders” This review discusses the scalp microinfusion MMP® technique for hair loss treatment and reports no new results; it emphasizes the need for more standardized studies.