May 2022 in “Acta scientific dental sciences” This article discusses the use of platelet concentrates in regenerative surgeries for periodontal and bone defects but presents no new clinical results, emphasizing their potential benefits over traditional methods.
February 2024 in “Cureus” This study found that combining platelet-rich plasma therapy with topical minoxidil improved hair shaft diameter and hair follicle density more effectively than PRP alone in men with androgenetic alopecia.
101 citations
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December 2014 in “Stem Cells and Cloning Advances and Applications” This article reviews the potential and current applications of adult oral stem cells in regenerative medicine, highlighting promising animal model results but noting that few human clinical trials have yet been conducted.
This dissertation describes using skull bone for upper jaw reconstruction, leading to less pain and the possibility of immediate implant placement compared to traditional methods.
54 citations
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June 2018 in “Nutrients” This review discusses the diverse extra-intestinal manifestations of celiac disease in children and reports no new clinical results; the authors note differences in symptom prevalence and resolution compared to adults.
28 citations
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January 2008 in “Journal of medical investigation” This study found that Sp6 overproduction in ameloblast-lineage cells increased cell proliferation and ameloblastin expression, suggesting that Sp6 promotes amelogenesis by inhibiting follistatin gene expression.
17 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” This study reported that newly developed quaternary ammonium chitosan/carboxymethyl starch/alginate sponges effectively inhibit bacterial growth and promote rapid hemostasis in wound management after tooth extraction in animal models, showing significant promise for clinical use in preventing complications like dry socket.
5 citations
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November 2024 in “Advanced Science” This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.
October 2025 in “Clinical and Experimental Pediatrics” In this case report and literature review, researchers identified a novel mutation in the CLDN1 gene linked to neonatal ichthyosis-sclerosing cholangitis syndrome and found that its phenotype varies widely, suggesting a multidisciplinary approach is crucial for management.
September 2025 in “The Professional Medical Journal” In this study, 5mg oral minoxidil given daily for 24 weeks significantly increased hair thickness and scalp appearance among 27 male patients with androgenetic alopecia, although some experienced side effects like hypertrichosis and mild headaches.
December 2024 in “Health Science Reports” This review found that topical metformin shows potential as a treatment in dentistry for periodontitis and in dermatology for conditions like wound healing and acne, but results for melasma are inconsistent.
January 2024 in “Wiadomości Lekarskie” This review explores the integration of robotics in dentistry, highlighting their use in oral surgery, prosthetics, endodontics, and orthodontics, and discusses the current state of clinical research along with potential future advancements in the field.
December 2023 in “British journal of oral & maxillofacial surgery/British journal of oral and maxillofacial surgery” This review discusses the role and function of platelet-rich plasma (PRP) in third molar extractions and reports no new clinical results.
This review explores the clinical applications of platelet rich plasma therapies across several fields and suggests potential future research directions for cord blood platelet rich plasma.
January 2023 in “Medicines” This study reported that using micronized-gingival connective tissues appeared safe and showed initial efficacy for reconstructing peri-implant soft tissues, suggesting potential as an alternative to traditional grafting methods.
January 2023 in “Wiadomości Lekarskie” In this study, the researchers shared their experiences with using local intracanal antibiotic therapy for treating endodontic bacterial infections, noting that current disinfectants, though effective, are highly toxic to human cells.
April 2017 in “International journal of current advanced research” This article discusses the importance of a balanced diet, emphasizing the need for varied nutrients for health and better organ function, but presents no new research findings.
83 citations
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January 2001 in “American journal of clinical dermatology” This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.
202 citations
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July 2022 in “Biomedicine & Pharmacotherapy” This review compiles and discusses the ethnomedicinal uses, pharmacological activities, and phytochemistry of pomegranate, suggesting potential future applications in drug discovery for various ailments but reports no new clinical results.
186 citations
,
February 2017 in “Cell Proliferation” This review suggests that omitting the proteolysis step and including tissue pieces in mesenchymal stem cell isolation may improve cell quality, reduce contamination risk, and lower costs and processing time in clinical applications.
175 citations
,
December 1980 in “Archives of Dermatology” In this study, researchers examined two new cases of trichothiodystrophy and observed that the condition is linked to decreased synthesis of high-sulfur matrix proteins in hair.
130 citations
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January 2005 in “American Journal of Clinical Dermatology” This review discusses the dermatologic symptoms associated with severe eating disorders like anorexia nervosa and bulimia nervosa and how they can aid in early diagnosis, without reporting new results.
64 citations
,
January 2001 in “Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy” This review discusses the diverse pharmacological activities of misoprostol across multiple health conditions but reports no new clinical data, highlighting potential applications beyond its traditional uses.
55 citations
,
May 1970 in “New England Journal of Medicine” This study found that scurvy is associated with the development of Sjögren's syndrome symptoms, which resolved with ascorbic acid repletion.
42 citations
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August 2008 in “Stem Cells and Development” This study found that mesenchymal cells from adult mouse whisker follicles differentiated into odontoblast-like cells, demonstrating odontogenic potential in a specialized microenvironment both in vitro and in vivo.
36 citations
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October 2016 in “Bone” This case report describes a male patient with aromatase deficiency, revealing that a c.628G>A mutation can lead to varied clinical features, such as low bone mass and normal metabolic profiles.
28 citations
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December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
27 citations
,
May 2011 in “Current Opinion in Ophthalmology” This study reports that a new transplantation technique using tissue-engineered stem cells successfully reconstructed corneal epithelium in an animal model of severe ocular surface disease.
27 citations
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February 1988 in “Journal of the American Academy of Dermatology” This case report describes a patient with ulerythema ophryogenes who had developmental and physical anomalies and showed no improvement with topical or oral isotretinoin treatments.
18 citations
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January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.