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A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

New genes and pathways are important for testosterone production and male sexual development.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Ciproterone acetate improves hair regrowth and acne in most female patients.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Both estrogens and androgens are important for health in both males and females.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

New treatments for male hypogonadism are effective and should be personalized.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The document concludes that more research is needed to fully understand the causes of PCOS.

Adult acne is more common in women, often linked to hormones, and can be harder to treat.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Minoxidil effectively treats female pattern hair loss.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.