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This study presents a hypothesis that the EDAR V370A allele was positively selected in East Asian populations due to the stable aquatic resources in Late Pleistocene northern China, which may have offset the allele's metabolic costs and provided a selective advantage.

In this case study, DDS treatment for LABD was complicated by hemolytic anemia and alopecia, suggesting the need for careful monitoring of these potential side effects.

This study developed a Hyaluronic acid-Carbopol liposomal gel co-loaded with Adapalene and Clindamycin Phosphate, optimized to improve skin penetration and anti-acne efficacy, showing enhanced drug delivery, superior clinical effectiveness, and excellent skin tolerability compared to commercial formulations.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

This study found that the DPP-4 inhibitor linagliptin slowed the progression of premature aging characteristics in klotho-/- mice, including improved body weight, cognitive function, and hair retention.

This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.

The study found that stratum corneum thickness and total epidermal lipid content influence the permeation rates of certain nonsteroidal anti-inflammatory drugs in various animal skin models, and suggests porcine skin as an effective human replacement in diffusion experiments.

In this study, liposome-encapsulated thioglycolic acid improved hair perming by enhancing the penetration of perm solutions, resulting in a stronger S-shaped wave and higher cysteine content compared to the control.

This study found that a spontaneous deletion in the Dsg3 gene of mice leads to hypomorphic desmoglein 3 expression, resulting in severe immunodeficiency, cyclic hair loss, and wasting disease, without causing the blistering typical of pemphigus vulgaris.

In this mouse study, researchers found that the Jieduquyuziyin prescription may lessen lupus-like symptoms and atherosclerosis by inhibiting TLR9/MyD88 signaling and promoting cholesterol efflux.

In this study, researchers developed a simplified and reliable method to prepare human hair shaft samples, achieving over 75% protein extraction efficiency and improved keratin sequence coverage, with the approach showing high reproducibility across different labs and operators.

In this review, researchers noted that liposomes, due to their ability to stabilize and target drugs, are effective carriers for treating various dermatological conditions such as acne and psoriasis when applied topically.

This study found that the AtSfh1 protein in Arabidopsis is essential for phosphatidylinositol-4,5-bisphosphate signaling crucial to polarized root hair growth, utilizing both phosphatidylinositol and phosphatidylcholine-binding activities.

This article discusses the potential of phospholipase A2 inhibition as a therapeutic strategy for inflammatory skin diseases and emphasizes the need for further exploration of its role and administration methods.

This review discusses the role of phospholipases in skin and hair health, suggesting that understanding their molecular control could inform new treatments for related conditions, but it presents no new clinical results.

This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.

This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.

This research highlights that lip feminization, an essential aspect of facial feminization surgeries for transgender women, lacks dedicated studies, underscoring a significant gap in understanding and optimizing this procedure for gender expression.

This study observed that hairless rat skin was more permeable to mannitol and progesterone than hairy rat skin, indicating that follicular structures significantly impact percutaneous absorption.

This study found that hydrogenated palm oil effectively conditions damaged hair by preventing water-induced swelling, with TOF-SIMS analysis showing that its component tripalmitin penetrates the hair's cuticle and outer cortex.

This review discusses various methods for processing and separating human skin samples for research purposes, evaluating factors like processing time and cell viability, but reports no new experimental findings.

This case report describes a 52-year-old black woman with diffuse scalp swelling and thinning hair attributed to a large increase in the thickness of scalp subcutaneous fatty tissue.

This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.

This study found that a peptide treatment using Protein disulphide isomerase improved the mechanical and thermal properties of over-bleached hair by promoting deeper peptide penetration and attachment.

Nelfb is essential for dermal fat development and survival.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

In this study, researchers propose that the EDAR V370A allele's positive selection in East Asian populations may be linked to stable aquatic resources from Late Pleistocene ecosystems in northern China, suggesting a "nutritional niche construction" framework where these resources offset the allele's metabolic costs.

In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.