2 citations,
September 2002 in “Journal of Endocrinological Investigation” The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
1 citations,
December 2019 in “Frontiers in endocrinology” Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
1 citations,
January 2016 in “Journal of Microbial & Biochemical Technology” The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
July 2024 in “Reproductive health of woman” Girls conceived via assisted reproductive technologies show early puberty signs and larger ovaries.
November 2022 in “Scientific Reports” Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.
November 2022 in “Journal of the Endocrine Society” A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.
May 2021 in “Journal of the Endocrine Society” A rare ovarian cancer with a good outlook was found in a woman with unusual hair growth and abdominal symptoms.
April 2021 in “Journal of evolution of medical and dental sciences” Women with PCOS have higher levels of certain androgens, which are good at predicting excess hair growth.
January 2017 in “Clinical & medical biochemistry” Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
May 2017 in “Endocrine Abstracts” Men with early hair loss and certain health factors may have a higher risk of developing reproductive issues, similar to polycystic ovary syndrome in women.
13 citations,
August 1997 in “Steroids” Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
March 2014 in “Human Physiology” DHEA improved brain function and behavior in old monkeys and had additional health benefits.
87 citations,
March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
22 citations,
January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
11 citations,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
12 citations,
December 2020 in “Comprehensive psychoneuroendocrinology” Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.
451 citations,
March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
251 citations,
October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
82 citations,
January 2000 in “Hormone Research in Paediatrics” DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.
46 citations,
August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
33 citations,
January 2013 in “Dermatology” Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
January 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Norethisterone (jenapharm) therapy is effective for endometrial cancer.
32 citations,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
24 citations,
September 1996 in “Mycoses” Androgenic steroids can slow down or stop the growth of certain skin fungi.
16 citations,
March 2014 in “Journal of the European Academy of Dermatology and Venereology” Korean patients with PCOS often have skin problems like acne and excess hair, with different symptoms based on their specific PCOS type.
13 citations,
March 2019 in “Physiological Research” Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.