Characteristics of Physical and Sexual Development of Girls Conceived by Assisted Reproductive Technologies

    July 2024 in “ Reproductive health of woman ”
    İ.R. Mustafayeva, E.M. Aliyeva, M.A. Garashova, A.N. Khudiyeva, E.V. Bayramova
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    TLDR Girls conceived via assisted reproductive technologies show early puberty signs and larger ovaries.
    The study examined 16 teenage girls conceived via assisted reproductive technologies (ART) and compared them to 25 girls born from spontaneous pregnancies. Results showed that girls conceived with ART had significantly increased ovarian size and higher levels of LH, DHEA-S, and E2, indicating hyperandrogenism and hyperestrogenism. These girls also exhibited premature development of secondary sexual characteristics and pronounced hair growth. However, their carbohydrate metabolism, liver enzyme activity, and kidney function were similar to those of girls born from spontaneous pregnancies.
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