Free Androgen Index: Marker of Premature Androgenetic Alopecia in Men

    January 2016 in “ Journal of Microbial & Biochemical Technology ”
    Sarita Sanke, Chet Ram, er, Taru Garg, Anju Jain
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    TLDR The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
    In 2016, a study involving 57 men with premature androgenetic alopecia (AGA), a condition causing hair loss before age 30, was conducted to evaluate various androgenic hormones. The study compared the serum concentrations of Testosterone, DHEAS, and SHBG, and calculated the Free Androgen Index (FAI) of these men with age and sex-matched controls. The results indicated significant differences in the mean values of all three indicators for androgen status in cases compared to the controls. The study found that FAI and DHEAS were better predictors of hyperandrogenism than testosterone, concluding that FAI is the best marker of a person's androgen status and can be considered as the marker of premature AGA.
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      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 2 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

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