The Efficacy of an Adjuvant Norethisterone (Jenapharm) Therapy in Endometrial Cancer

January 1987 in “ Journal of steroid biochemistry/Journal of Steroid Biochemistry ”

W Krafft, Renate Steuckardt, H Behling, Eva-Maria König, D Brückmann, J Kademann, G Schmeisser

TLDR Norethisterone (jenapharm) therapy is effective for endometrial cancer.

The document from 1987 discusses the role of androgens in the development and severity of acne, noting that it can be associated with various endocrinopathies such as polycystic ovarian syndrome, ovarian tumors, or adrenal hyperplasia or tumors. These conditions may be suspected in patients with sudden onset acne, hirsutism, menstrual irregularities, cushingoid facies, acanthosis nigricans, patterned hair loss, or a deepened voice. In such cases, it is recommended to test for serum-free and total testosterone, dehydroepiandrosterone, luteinizing hormone, and follicle stimulating hormone, and to provide appropriate referral and long-term follow-up. The document also outlines hormonal therapies for acne, which include androgen receptor blockers (spironolactone, cyproterone acetate, chlormadinone, flutamide), adrenal androgen production blockers (glucocorticoids), and ovarian androgen production blockers (gonadotropin-releasing agonists and oral contraceptives), providing practical guidelines for treatment.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 828 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 55 upvotes 1 year ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community How does hair loss and recovery work?

in Chat 12 upvotes 4 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Why balding gets worse in every generation?

in Chat 81 upvotes 7 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 1 year ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

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