January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
18 citations
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January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
1 citations
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February 2023 in “Pharmaceutics” This study suggests that UVA-responsive nanocapsules may provide an effective method for skin antisepsis by releasing ethanol and reducing microorganisms within hair follicles on ex vivo porcine ear skin.
2 citations
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March 2019 in “PubMed” This case report describes successful treatment of folliculitis decalvans in a 41-year-old woman using oral fusidic acid, leading to clinical improvement and no recurrences after six months.
3 citations
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September 2013 in “Bioscience Biotechnology and Biochemistry” In this study, the type II subunit of porcine hair keratin was found to significantly inhibit the differentiation of PC12 neural cells compared to the crude extract and type I subunit, although cell proliferation was unaffected.
2 citations
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September 2023 in “Foods” In this study, researchers developed microcapsules and effervescent tablets containing policosanol from insect wax, achieving high encapsulation efficiency and rapid water dispersion, effectively addressing the challenges of solubility and psychological acceptance in consuming insect-based lipids.
1 citations
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January 2025 in “Frontiers in Pharmacology” This review discusses the therapeutic and pharmacological potential of total glucosides of paeony in dermatological treatment and notes the need for more rigorous scientific studies.
5 citations
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September 2024 in “Biomolecules and Biomedicine” This study found that total glucosides of paeony (TGP) reduced hair loss and inflammation in alopecia areata mice by inhibiting cellular pyroptosis.
October 2012 in “Organic Process Research & Development” This study developed a new crystallization method using solid solution formation to purify finasteride by effectively removing contamination with dihydrofinasteride.
1 citations
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January 1989 in “Carcinogenesis” This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.
November 2022 in “Journal of Investigative Dermatology” This study found that stimulating the olfactory receptor OR2A4/7 with cyclohexyl salicylate promoted human hair growth and increased progeny of hair follicle epithelial stem cells in an ex vivo setting.
June 2026 in “Materials Today Bio” This study reported that a decellularized porcine amniotic membrane hydrogel can alleviate inflammation and promote tissue repair in a UVB-induced skin inflammation model, suggesting its potential as a regenerative treatment for photodamage-associated skin injuries.
6 citations
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June 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.
2 citations
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September 2020 in “Swedish Journal of BioScience Research” This study found that chitosan from Lucilia cuprina improved burn healing in diabetic mice, promoting wound closure, epidermal remodelling, and collagen deposition, while also demonstrating antibacterial properties.
January 2024 in “Advanced Science” In this study, researchers used a chemical cocktail and hydrogel microspheres to successfully guide fibroblasts into dermal papilla cells, promoting wound healing and in situ hair follicle regeneration while reducing scar formation, in both in vitro and in vivo experiments.
43 citations
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July 2016 in “European journal of pharmaceutical sciences” This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.
2 citations
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January 2019 in “Recent Advances in Biology and Medicine” This study found that a combination of 5% DMSO and BSA minimizes toxic effects on the cytogenetic stability of dermal papilla cells during cryopreservation.
1 citations
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April 2009 in “Expert Review of Dermatology” This study found that the once-daily gel combining calcipotriene and betamethasone dipropionate was more effective and faster in treating scalp psoriasis compared to individual treatments, with a similar safety profile.
15 citations
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June 2019 in “Biochemical Journal” This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.
January 2017 in “Rasayan journal of Chemistry” This paper describes a new scalable synthesis method for Dutasteride, highlighting its potential for large-scale commercial production.
January 2026 in “Advanced Healthcare Materials” This study highlights a treatment approach using dissolving microneedle patches containing nanomicelles formed by stevioside to enhance the therapeutic efficacy and safety of poorly soluble drugs, as depicted in the cover illustration with luxuriant hair symbolizing its potential effectiveness.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a herbal anti-dandruff shampoo containing fenugreek and hibiscus and found it had good cleansing action, stable foam, satisfactory pH, and caused no skin irritation, suggesting it may be an effective alternative to synthetic shampoos.
2 citations
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November 2007 in “Journal of Investigative Dermatology” This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.
12 citations
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November 2022 in “Toxics” This review describes how liver and kidney diseases and diabetes may affect ethyl glucuronide levels in hair, impacting forensic and clinical interpretations, but reports no new experimental results.
66 citations
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October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.
30 citations
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May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
47 citations
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September 1997 in “Journal of Pharmaceutical Sciences” This study found that cationic lipid-based formulations enhanced the delivery of large molecules into hair follicles in human scalp skin, with potential to reach pharmacologically active concentrations in the hair bulb.
August 2025 in “ACS Omega” This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated a polyherbal shampoo from plant extracts, finding it showed effective antifungal properties against dandruff-causing agents like Malassezia species while providing protective and conditioning effects on hair cuticles, indicating its potential as a natural alternative for dandruff management.
May 2024 in “Journal of Agricultural and Food Chemistry” In a study using mice, researchers observed that Cacumen platycladi fermented with Lactiplantibacillus plantarum CCFM1348—both as postbiotics and synbiotics—promoted hair growth, potentially by engaging the Wnt/β-catenin signaling pathway and enhancing growth factor expression.