2 citations
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June 2023 in “Clinical Cosmetic and Investigational Dermatology” In this study, post-treatment with DCO was found to speed up epidermal wound healing after micro-needling of 3D skin models while maintaining the treatment's immunostimulatory benefits, potentially optimizing aftercare and reducing patient recovery time.
28 citations
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November 2018 in “American Journal of Medical Genetics Part A” This report describes a neurometabolic disorder linked to gain-of-function variants in the ODC1 gene, characterized by developmental delay, ectodermal abnormalities, and notable facial and neuroimaging features.
20 citations
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December 1995 in “Veterinary Dermatology” This study identified a marked reduction in melanin in the hair of Yorkshire Terriers with Colour Dilution Alopecia and proposed a new pathogenetic mechanism based on these observations.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
18 citations
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January 2010 in “Dermatology Research and Practice” This case report describes a 30-year-old Brazilian male who developed vitiligo lesions following diphencyprone therapy for alopecia areata.
November 2024 in “Stem Cell Research & Therapy” A new method improves the isolation of hair follicle cells for better hair growth research.
94 citations
,
July 1991 in “Clinical endocrinology” In this study, cyproterone acetate at 2 mg daily was found to be as effective as higher doses in reducing hair growth for hirsute women over 12 months.
15 citations
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June 2015 in “F1000Research” This study examined immune responses to Diphencyprone and found that its induced skin reactions have higher levels of negative immune regulators compared to psoriasis, suggesting differences in immune regulation may contribute to psoriasis chronicity.
5 citations
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January 2014 in “Hospital pharmacy” This case report suggests that frequent application of diphenylcyclopropenone 2% solution to the scalp for alopecia areata may lead to scalp angioedema.
41 citations
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November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
4 citations
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September 2024 in “BMC Cancer” In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.
August 2025 in “Therapeutics” In this study, low concentrations of DMSO were found to decrease androgen receptor expression and inhibit the migration of prostate cancer cells, suggesting potential as an anticancer therapy.
This study demonstrated that the differential wetting characterization (DWC) method can effectively differentiate changes in the wetting properties of hair fibers after chemical or physical treatment.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study suggests that alkaline phosphatase-regulated expression of CCL5 contributes to the trichogenicity of human dermal papilla spheres.
6 citations
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January 2024 in “Annals of Dermatology” In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.
44 citations
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February 2015 in “Journal of the American Academy of Dermatology” This study found that combination therapy with diphenylcyclopropenone and anthralin was more effective for complete hair regrowth in chronic extensive alopecia areata than diphenylcyclopropenone alone, despite more common side effects.
45 citations
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March 1997 in “Journal of Investigative Dermatology” TCDD changes skin gene expression and may harm skin health.
48 citations
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June 2000 in “Japanese Journal of Cancer Research” This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
8 citations
,
January 2018 in “Journal of Analytical Methods in Chemistry” This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.
18 citations
,
January 2021 in “Theranostics” This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.
13 citations
,
September 2010 in “Journal of Dermatological Science” Researchers made a cell line that grows quickly and can help with hair growth research.
March 2024 in “Stem cell research & therapy” This study found that conditioned medium from human dental pulp stem cells (particularly under hypoxic conditions) improved keratinocyte survival and hair regrowth in a chemotherapy-induced alopecia mouse model and did not promote tumor growth, suggesting potential for safe therapeutic use.
January 2020 in “International Journal of Research in Pharmacy and Chemistry” This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.
11 citations
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August 1948 in “Journal of Investigative Dermatology” In this study, oral calcium pantothenate was associated with improvement in the inflammatory phase of discoid lupus erythematosus of the scalp, with the most marked response observed in subacute cases.
26 citations
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January 1992 in “Carcinogenesis” This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.
July 2025 in “Scientific Reports” This study found that dermal papilla cell-conditioned medium can protect against UV-induced skin aging in a mouse model by modulating ferroptosis pathways, highlighting its potential for treating oxidative stress-related skin conditions.
11 citations
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October 2018 in “The Journal of Dermatology” This study suggests that decorin may help maintain hair follicle stem cells and its reduced expression could contribute to age-related hair loss.
June 2024 in “International Journal of Pharmaceutical Quality Assurance” This study established a new reverse-phase high-performance liquid chromatography method to accurately and precisely quantify silodosin and dutasteride in mixtures, meeting International Council of Harmonization validation criteria for stability, sensitivity, and recovery.
4 citations
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October 2021 in “Journal of Clinical Medicine” This study found that individuals with heterozygous truncation-type variants in the *DSP* gene exhibit lower skin temperature and higher transepidermal water loss, with specific microscopic skin changes and pseudomonilethrix.
15 citations
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November 2016 in “Journal of The American Academy of Dermatology” This article discusses the potential of trichoscopy in diagnosing and treating dissecting cellulitis of the scalp and emphasizes the need for early diagnosis to prevent progression but reports no new clinical results.