Dermal Papilla Cells-Conditioned Medium Attenuates Oxidative Stress-Induced Senescence Via Ferroptosis Inhibition

    July 2025 in “ Scientific Reports ”
    Zhengang Ru, Yu Wu, Qian Qu … Zhiqi Hu
    Studysummary This study found that dermal papilla cell-conditioned medium can protect against UV-induced skin aging in a mouse model by modulating ferroptosis pathways, highlighting its potential for treating oxidative stress-related skin conditions.
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    1. Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging Skin research and technology · 2023
    2. Ficoll Density Gradient Sedimentation Isolation of Pelage Hair Follicle Mesenchymal Stem Cells From Adult Mouse Back Skin: A Novel Method for Hair Follicle Mesenchymal Stem Cells Isolation Stem cell research & therapy · 2022
    3. Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase Frontiers in Cell and Developmental Biology · 2022
    4. Electrical Stimulation to Human Dermal Papilla Cells for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2022
    5. Effects of UV-Induced Photoaging on the Hair Follicle Cycle of C57BL6/J Mice Clinical, cosmetic and investigational dermatology · 2021
    6. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021
    7. Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration Journal of Advanced Research · 2020
    8. Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth Theranostics · 2020
    9. ADSCs Inhibit Photoaging and Photocarcinogenesis-Related Inflammatory Responses and Extracellular Matrix Degradation Journal of Cellular Biochemistry · 2019
    10. An Important Role of Cutaneous Lymphatic Vessels in Coordinating and Promoting Anagen Hair Follicle Growth PLOS ONE · 2019
    11. Dental Derived Stem Cell Conditioned Media for Hair Growth Stimulation PLOS ONE · 2019
    12. Methods for the Isolation and 3D Culture of Dermal Papilla Cells from Human Hair Follicles Experimental Dermatology · 2017

    Related research 1

    1. Co-Culture of Human Hair Follicles and Dermal Papillae in a Collagen Matrix The Journal of Dermatology · 1990