ADSCs Inhibit Photoaging and Photocarcinogenesis-Related Inflammatory Responses and Extracellular Matrix Degradation
August 2019
in “
Journal of Cellular Biochemistry
”
adipose-derived stem cells ADSCs photoaging photocarcinogenesis UVB irradiation inflammatory markers MMP2 MMP13 phospho-NF-κB p65 Nlrp3 VCAM-1 TGF-β2 α6 integrin CD34 collagen I skin barrier function hair follicle stem cell activity extracellular matrix degradation stem cells UVB inflammation collagen skin barrier hair follicle activity
Studysummary This study found that adipose‐derived stem cells can restore skin barrier function and inhibit photoaging-related responses in UVB-irradiated mice, suggesting a potential therapeutic role in managing skin photoaging.
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