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Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Personalized treatments for hair loss are becoming more effective by using genetic information.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Hair loss in men treated best with early medication or transplant, new treatments researched.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Spironolactone helps regrow hair in women with hair loss.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.