40 citations
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January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
60 citations
,
May 2014 in “British Journal of Dermatology” This study found that caffeine enhanced hair growth and keratinocyte proliferation in human hair follicles, with female follicles showing greater sensitivity than male ones.
August 2020 in “Journal of Shahid Sadoughi University of Medical Sciences” This review discusses the role of oxidative stress in polycystic ovary syndrome and reports no new clinical results; the authors highlight the importance of understanding these mechanisms for prevention and treatment strategies.
April 2026 in “International Journal of Biological Macromolecules” 2 citations
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April 2023 in “American Journal of Dermatopathology” This study suggests that central centrifugal cicatricial alopecia may involve a CD4-predominant T-cell process with potential PD1/PDL1 pathway involvement, indicated by increased caspase 3 expression and loss of PDL1.
5 citations
,
February 2008 in “Experimental Dermatology” In this study, topical application of Cyclosporin A on mice skin induced hair growth by transitioning follicles from telogen to anagen, but no effect was observed on cultured human hair follicles.
28 citations
,
December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
2 citations
,
April 2017 in “PubMed” This review discusses the connection between hair follicles and dermal adipose tissue, suggesting that improving the adipogenic environment could be important for treating alopecia and enhancing hair restoration procedures, but reports no new results.
September 2010 in “International Journal of Cosmetic Science” This study describes a microfluorometric method to quantify lipid removal and reattachment on human hair during light exposure and chemical treatments, altering hair surface properties from hydrophobic to hydrophilic.
April 2026 in “Cytotherapy” This study identifies macrophage-mediated immune signaling as a crucial factor in activating hair follicle stem cells and promoting hair regeneration, offering a new model for testing regenerative therapies for alopecia.
54 citations
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December 2004 in “PubMed” This study suggests that topical Cyclosporin A formulations, with or without a penetration enhancer, effectively stimulated hair regrowth in a rat model of alopecia areata.
25 citations
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January 2014 in “Annals of Dermatology” Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.
12 citations
,
April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
6 citations
,
September 2015 in “Journal of Medicinal Chemistry” This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.
May 2010 in “Europe PMC (PubMed Central)” This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.
September 1995 in “PubMed” This study found that ozonized autohaemotherapy improved the hair cycle in individuals with androgenetic alopecia.
9 citations
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June 1947 in “Analytical Chemistry” Cold waving solutions quickly reduce cystine to cysteine in hair.
19 citations
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July 2017 in “PLoS ONE” This study suggests that passage number significantly affects in silico scratch assay results, highlighting the importance of reporting passage number for reproducibility in cell culture experiments.
403 citations
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December 2018 in “Cell stem cell” This study suggests that phenotypic plasticity, including processes like dedifferentiation and transdifferentiation, plays a crucial role in cancer initiation, progression, and therapy resistance, broadening our understanding of cancer dynamics and potential treatment strategies.
April 2017 in “Journal of Investigative Dermatology” This study found that anagen hair follicles can quickly regenerate after radiation damage by forming new progenitor cells outside the bulge, bypassing the need for telogen entry.
28 citations
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November 2012 in “Experimental dermatology” This study suggests that mTORC1 may play a role in regulating the timing of hair growth cycle phases, particularly the initiation of the anagen phase.
4 citations
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January 2011 in “Cell stem cell” This study reveals that stem cell descendants in mouse hair follicles can return to their niche to retain stemness and function as primary stem cells for future hair cycles.
July 2024 in “Journal of Investigative Dermatology” Brepocitinib improves cicatricial alopecia and reduces key immune markers.
13 citations
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October 2017 in “Bioorganic & Medicinal Chemistry” This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.
March 2003 in “International Journal of Antimicrobial Agents” March 2026 in “Tissue Engineering and Regenerative Medicine”
January 2023 in “Hormone and Metabolic Research” This review discusses drug repositioning as a promising strategy for developing treatments for cardiometabolic disorders and reports no new clinical results.
2 citations
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August 2019 in “Turkish Journal of Chemistry” This study reported that CoFe2O4 magnetic nanoparticles efficiently catalyzed the synthesis of minoxidil from 2,6-diamino-4-chloro-pyrimidine N-oxide, achieving a 95% yield with sustained reusability.
148 citations
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October 1997 in “Journal of Investigative Dermatology” TGF-β receptors are crucial for hair follicle development.