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This study found a significant discordance between clinical symptoms and dermatoscopic signs with histopathological inflammation in patients with LPP and AFF, affecting diagnostic and therapeutic approaches.

This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.

This review discusses the function and pathology of hair follicles and highlights the potential of using dogs as a model to study human hair and stem cell disorders, but presents no new experimental results.

This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.

This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.

In this study, disrupting the epidermal growth factor receptor in mice led to abnormal hair and skin development, characterized by disorganized hair follicles and systemic disease, providing a model for understanding EGFR's role in skin biology.

Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.

This article discusses genetic hair disorders in children, outlining diagnostic approaches and highlighting the significance of distinguishing isolated hair defects from those associated with syndromes, but it reports no new clinical results.

This review highlights the critical role of mitochondrial dysfunction in hair loss, particularly androgenetic alopecia, and explores potential therapies targeting mitochondrial pathways to improve hair health, underscoring the need for further research in this area.

This article discusses various aspects of hair and scalp health, ancient philosophical perspectives on hair, and causes of hair disorders in children, without reporting new clinical results.

This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.

Mutations in the hHb6 gene cause the hair disorder monilethrix.

In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.

This review discusses the various determinants of hair quality in healthy individuals and reports no new clinical results; the authors emphasize the need for independent trials with standardized outcomes.

This article highlights that trichorrhexis nodosa, a common type of hair breakage, is influenced by factors like heat styling and chemical treatments, with potential FDA action on formaldehyde usage in hair products potentially altering its treatment approach.

In this study, researchers used atomic force microscopy to capture and analyze morphological changes in the surface of healthy hair, identifying features such as pitting and rod-shaped macro-fibrillar elements, which could inform future research on hair conditions and care.

This review discusses hair shaft disorders, noting the lack of specific treatments and recommending general care practices to prevent hair damage, with some improvement possible during puberty or with treatments like minoxidil.

This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.

This study found that the Dun camouflage color in horses is due to TBX3 expression, which causes uneven pigment deposition, whereas non-dun coat colors result from regulatory mutations affecting TBX3 expression.

This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.

This study reviews the biology and cosmetic treatment of hair, emphasizing future advancements in safer, more effective procedures to meet consumer needs for hair care.

This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.

A new mutation, Glu402Lys, in hair keratin is linked to variable symptoms of monilethrix.

This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This review discusses advances in drug delivery systems to enhance oleanolic acid's bioavailability and therapeutic potential but reports no new clinical results.

This study in mutant mice found that Bmpr2 and Acvr2a are individually redundant, but together essential for normal hair follicle development, with their reduction causing rapid hair cycling and graying.

This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.

This study reviews current research to better understand how various environmental and lifestyle factors, collectively known as the exposome, impact hair health and aging, acknowledging that the detailed mechanisms remain partially understood.

This article presents a comprehensive overview of hair microscopy techniques and their diagnostic potential for systemic and cutaneous disorders, emphasizing its usefulness in resource-limited settings and highlighting the underutilization of this non-invasive method due to lack of awareness.