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In Brazil in 2018, the most common skin issues were acne, photoaging, and nonmelanoma skin cancer, with treatments often including topical medications and sunscreen.

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

Looking at skin can help find and treat serious diseases early.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Minoxidil may help hair growth by stopping immune system attacks on hair follicles.

Some skin diseases and their treatments can negatively affect male fertility.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Hair loss affects women's self-esteem; treatments like minoxidil can help.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Animal research has greatly advanced dermatology.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

New therapy helps treat hair loss.

New therapy helps treat hair loss.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Tempol is safe and may prevent hair loss from brain radiotherapy.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.