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Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Different types of skin cells play specific roles in development, healing, and cancer.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Special fiber materials boost the healing properties of certain stem cells.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Telocytes might help with skin repair and regeneration.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.