November 2015 in “Journal of the Korea Academia-Industrial cooperation Society” This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.
28 citations
,
February 2007 in “Cancer Research” This study found that inhibiting C/EBP transcription factors in mouse skin reduced papilloma formation and caused systemic hair loss, suggesting C/EBP may be a potential therapeutic target.
May 2015 in “Plastic and Reconstructive Surgery” This article introduces a novel, inexpensive hair preparation technique using glove-finger sheaths to secure and protect hair during calvarial surgery, reducing procedure time and hair damage without the need for full scalp shaving.
3 citations
,
December 2021 in “Proteins” This study found that straight crimp mutant wool differs from crimpy wool in the layout of cortical cells and the relative proportions of keratin and keratin-associated proteins.
14 citations
,
July 2021 in “Biomolecules” This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.
6 citations
,
March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
January 2011 in “The Chinese Journal of Dermatovenereology” This study found that curcuma anti-acne gel reduced comedo formation and improved skin characteristics in a rabbit ear acne model, showing potential for treating acne.
5 citations
,
January 2007 This study found that topical application of Citrullus colocynthis extracts reduced hair growth initiation and completion times in albino rats and resulted in similar hair follicle anagen phase activation as minoxidil.
314 citations
,
April 2010 in “Developmental Cell” This study found that in mice, inactivating beta-catenin in the dermal papilla reduces hair follicle progenitor proliferation and disrupts the hair cycle.
23 citations
,
August 1975 in “Experimental Biology and Medicine” This study found that supplementing pregnant and lactating mice with high dietary copper improved survival and physical traits in mice carrying the crinkled mutation, suggesting copper's role in modulating gene expression.
1 citations
,
September 2023 in “Genes” This study found no significant difference in CUX1 core promoter methylation levels between different lambskin patterns in Hu sheep, suggesting other mechanisms influence CUX1 expression related to hair follicle development.
3 citations
,
August 2022 in “Molecules/Molecules online/Molecules annual” This study found that microbial adenosine and biotin treatments derived from Staphylococcus epidermidis Cicaria culture may help inhibit hair loss by maintaining the hair's growth phase.
66 citations
,
October 2002 in “Human molecular genetics online/Human molecular genetics” This study found that a nonsense mutation in the Cst6 gene of mice leads to severe skin and hair abnormalities, suggesting that cystatin M/E is crucial for epidermal function and viability.
In this animal study, treatment with Trachyspermum copticum seed extract significantly altered IL-1 and KGF/FGF-7 gene expression, improving dermatitis and hair growth in mice compared to controls and corticosteroids.
3 citations
,
July 2011 in “Folia Histochemica et Cytobiologica” This study concluded that the inner root sheath inhibits the expression of certain differentiation markers in hair bulbs, with calcium-induced changes paralleling those seen in hair follicle mid-segments.
2 citations
,
January 2019 in “Indian Dermatology Online Journal” This paper summarizes the foundation and proceedings of the first International Congress of SAARCUM, which addressed the growing issue of antifungal therapy failures in South Asia but reports no new research findings.
10 citations
,
November 2018 in “Genetics in medicine” This study identified a genetic variant in the CTS6 gene associated with a hypotrichosis syndrome, emphasizing the significant role of cystatin M/E in hair and skin health.
14 citations
,
April 2019 in “Saudi pharmaceutical journal” This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.
10 citations
,
November 2016 in “International Journal of Cosmetic Science” This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.
July 2024 in “Journal of Investigative Dermatology” Brepocitinib improves cicatricial alopecia and reduces key immune markers.
38 citations
,
February 1989 in “Journal of Investigative Dermatology” July 2025 in “Journal of Investigative Dermatology” 12 citations
,
July 2004 in “Molecular genetics and genomics” This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.
21 citations
,
August 2007 in “Experimental Dermatology” This study found that mice genetically modified to overexpress the serine protease inhibitor hurpin showed reduced UV-induced apoptosis but increased susceptibility to skin cancer after chemical carcinogenesis.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that CTCF is crucial for proper skin and hair follicle development in mice, affecting keratinocyte differentiation and gene expression in keratin loci.
22 citations
,
July 1998 in “Journal of Investigative Dermatology” This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.
3 citations
,
September 1973 in “Archives of dermatology” This study reports that daily topical application of a 0.05% tretinoin solution can eliminate the hair plugs and symptoms associated with trichostasis spinulosa.
October 2010 in “Journal of Drugs in Dermatology” This article introduces a modified surgical scalpel designed to minimize side effects in hair transplantation, proposing it as an ideal tool for removing the donor area.
3 citations
,
April 2015 in “Current problems in dermatology” This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.
14 citations
,
January 2004 in “Journal of Biochemical and Molecular Toxicology” This study found that sudden hair loss in guinea pigs may serve as a potential biomarker for subacute exposure to mustard gas, and pre-treatment with N-acetylcysteine could prevent this hair loss.