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This review reports on the potential for deucravacitinib, an oral TYK2 inhibitor approved for psoriasis, to treat various immune-mediated diseases, with emerging research suggesting possible uses in neurodegenerative diseases and certain cancers.

This correspondence discusses bias in expert medical testimony within workmen's compensation cases, emphasizing the author's objective approach, but provides no new empirical findings.

This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.

This article offers a viewpoint on hidradenitis suppurativa pathogenesis, suggesting that impaired Notch signalling from γ-secretase mutations may drive inflammation and link the condition to other Th17-driven diseases.

This review discusses baricitinib's applications for various inflammatory disorders and highlights its promising efficacy alongside potential adverse effects, advocating for further research before it becomes a standard treatment.

This study found that dysregulation of systemic Th1, Th2, and Th17 cytokines is associated with alopecia areata, with specific cytokines linked to disease activity and treatment response.

This article reviews the multifaceted roles of vitamin D beyond bone health and notes its potential involvement in reducing risks of certain cancers and autoimmune diseases, but it presents no new clinical results.

This review highlights the potential of regenerative medicine therapies, particularly stem cells, in treating a range of chronic diseases and injuries, while also discussing advancements and limitations in their application in Malaysia compared to other Asian countries.

This case report describes a patient with psoriasis, vitiligo, and alopecia areata who showed significant improvement in all conditions after treatment with ustekinumab, suggesting potential benefits of IL-12/23 blockade for these autoimmune diseases.

This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.

In this retrospective study, low-dose methotrexate was observed to be effective and well-tolerated in treating recalcitrant alopecia areata multiplex, achieving complete or near-complete hair regrowth in about 90% of patients despite some experiencing elevated liver enzymes and gastrointestinal discomfort.

In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.

This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.

This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.

This study found that the MIR34A rs2666433 (A/G) variant is linked to increased risk and severity of alopecia areata, and high circulatory miR-34a levels may play a role in the disease's pathogenesis.

In this genetic study, the researchers found that variants in the CLEC4D gene are significantly associated with the development of alopecia areata among individuals in the Jordanian population, pointing to a potential genetic influence on the disease's pathogenesis.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

This study highlights that hypoalbuminemia, often found in critically ill or elderly hospitalized patients, may increase morbidity, mortality, and hospitalization duration, suggesting specific conditions where oral or parenteral albumin supplementation should be considered.

This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.

The document explains various skin conditions and their treatments.

This study found that selectively targeting HDAC4 and HDAC7 in mice can reduce Th17 cell-mediated intestinal inflammation, suggesting a potential treatment approach for Th17-related inflammatory diseases like ulcerative colitis.

This paper reviews current and developing treatments for severe alopecia areata but reports no new clinical findings; the authors highlight the need for standardized treatment protocols.

This study suggests that personality plays a significant role in how psychological factors influence the onset and progression of alopecia areata, as well as its psychosocial impacts.

This report details the experiences gained during a pharmacy internship in both hospital and community settings, highlighting the preparation of sildenafil suspensions for hospital use, patient consultations on autoimmune conditions, and educational material creation in community pharmacy, alongside insights into diabetes and ADHD treatments.

During LIFEHOUSE, researchers documented distinct patterns of physical exam findings and biomarker abnormalities in 369 adult employees, which may aid clinicians in recognizing wellness challenges and preventing chronic diseases associated with aging.

This paper reviews the emerging potential of menstrual blood-derived mesenchymal stem cell extracellular vesicles in regenerative medicine, highlighting their promise for treating several diseases without providing new clinical results.

This article reviews the current ACR classification criteria for systemic lupus erythematosus, highlighting their dermatologic limitations, and proposes guidelines for a study to update these criteria.

This review discusses the use of recombinant cytokines as therapeutic agents in clinical settings and describes the range of cutaneous complications associated with their use, including both minor and severe skin reactions.

This review discusses the causes, clinical presentation, and management of anagen effluvium, emphasizing its psychological impact and the need for empathy and practical support, but reports no new results.

This narrative review highlights the crucial role of micronutrients and gut microbiota in thyroid function and suggests that nutritional imbalances may contribute to thyroid dysfunction or diseases.