research TGF-β2 and Collagen Play Pivotal Roles in the Spheroid Formation and Anti-Aging of Human Dermal Papilla Cells
Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
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research Loss of ERBB2 and ERBB3 Receptors Impacts Epidermal Differentiation in Mice
Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Specific Ectodermal Enhancers Control the Expression of Hoxc Genes in Developing Mammalian Integuments
The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.
research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
research Decoding The Role Of OsPRX83 In Enhancing Osmotic Stress Tolerance In Rice Through ABA-Dependent Pathways And ROS Scavenging
OsPRX83 helps rice survive stress by improving stress response and antioxidant activity.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research The Long Road Traveled in Hematopoietic Stem Cell Gene Therapy
The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
research Meeting Report: 68th Montagna Symposium on the Biology of Skin 'Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology'
The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
research Androgenetic Alopecia in Men: An Update on Genetics
Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.
research Cyclical Dermal Micro-Niche Switching Governs the Morphological Infradian Rhythm of Mouse Zigzag Hair
Mouse zigzag hair bends form due to a 3-day cycle of changes in hair progenitors and their environment.
research Cutaneous Responses to Systemic Iron: A Potential Role for Epidermal Turnover in Mammalian Iron Excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy
The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China
Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
research Epidermal Retinol Dehydrogenases Cyclically Regulate Stem Cell Markers and Clock Genes and Influence Hair Composition
Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Celsr1 And Celsr2 Exhibit Distinct Adhesive Interactions And Contributions To Planar Cell Polarity
Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
research Functional Enhancement Strategies for Immunomodulation of Mesenchymal Stem Cells and Their Therapeutic Application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research SbbHLH85, a bHLH Member, Modulates Resilience to Salt Stress by Regulating Root Hair Growth in Sweet Sorghum
The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.
research Topical Application of Newly Developed Pseudoceramide Improved Both Skin and Hair Barrier Functions
Applying pseudoceramide improved skin and hair health.
research Human and Animal Cells Under Influence of Different Lighting and Stimuli
Different light affects cell functions and can help treat skin conditions.
research Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat
DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.
research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research Oral Presentations: Findings from Dermatological Studies
The document concludes that an experimental drug may help wound healing in Epidermolysis Bullosa, links Hydroa vacciniforme to EBV, discusses diagnosing hair loss disorders, finds many children with eczema have allergies, reviews the safety of a skin medication in children, notes side effects of a Duchenne's treatment, and identifies a marker for pediatric mastocytosis.
research Calcium Regulation of Stem Cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition
Researchers found a genetic region that influences the number of coat layers in dogs.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Genetics of Hidradenitis Suppurativa
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
research PNKP Is Required for Maintaining the Integrity of Progenitor Cell Populations in Adult Mice
PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.