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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

Epigenetic mechanisms control skin development by regulating gene expression.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Notch signaling disruptions can cause various skin diseases.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Both drugs lower DHT levels, with GI198745 being more effective.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

Softer hydrogels help wounds heal better with less scarring.