July 2023 in “International Ayurvedic medical journal” Ayurvedic treatments showed promise in treating premature graying of hair without harmful effects.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
January 2017 in “Journal of Cosmetics, Dermatological Sciences and Applications” Chinese women's hair gets thinner and grayer with age, and scalp conditions change, especially after 40.
Surgical repigmentation can permanently restore color to white hair in vitiligo patients.
January 2015 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” Men with severe hair loss may have a higher risk of heart disease.
375 citations,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
130 citations,
September 1990 in “Journal of the American Academy of Dermatology” Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
117 citations,
August 2005 in “Ultramicroscopy” Human hair's strength and flexibility vary by ethnicity, damage, and treatment.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
111 citations,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
110 citations,
January 2014 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
99 citations,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
92 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
58 citations,
January 2006 in “Skin Pharmacology and Physiology” High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
52 citations,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
46 citations,
June 2013 in “Journal of structural biology” High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
42 citations,
June 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” PAI-2 helps in the maturation and protection of hair and nail cells.
35 citations,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
35 citations,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
35 citations,
July 2010 in “The FEBS journal” The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.
33 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
33 citations,
April 2009 in “Clinical and Experimental Dermatology” Psychological factors like depression may be more important than zinc, folate, and vitamin B12 levels in causing scalp pain in people with hair loss.
21 citations,
October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
20 citations,
August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
17 citations,
June 2019 in “The journal of immunology/The Journal of immunology” A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
16 citations,
January 2015 in “Forensic science international” The hair of two ancient Chilean mummies is well-preserved and contains high levels of heavy metals.
13 citations,
December 2001 in “Dermatologic therapy” Alopecia areata causes varying hair loss patterns, affecting hair, nails, and possibly glands, with treatment outcomes depending on disease duration and extent.
11 citations,
January 2015 in “Skin pharmacology and physiology” Eating collagen peptides may help with skin and hair growth.
11 citations,
October 2003 in “PubMed” Treatments with certain oils and resins make hair shinier, while zinc oxide and synthetic sebum make it duller.
10 citations,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.