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This review discusses the structure and assembly of the cornified cell envelope in stratified squamous epithelial cells and various disorders leading to barrier defects, but reports no new findings.

This study observed that the expression of certain keratins during human epidermal development marks the tissue's commitment to stratification and keratinization processes.

This study found that conditional knockout of N-WASP in keratinocytes of mice led to skin barrier defects, increased immune cell infiltration, and hyperproliferation of keratinocytes, indicating its crucial role in skin homeostasis.

In this study, application of salicylic acid solution on mouse skin showed histologic changes without causing wounds or inflammation, observed immediately and up to 48 hours after treatment.

This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.

The study reports that the AVET system showed higher efficiency in transfecting cultured human keratinocytes compared to SuperFect and PrimeFector, with AVET reaching levels of enzyme activity similar to normal cells in keratinocytes from lamellar ichthyosis patients.

This article describes the structure and components of hair cuticle cells and their intercellular junctions but reports no new clinical results.

This study found that keratin-associated proteins form part of the developing exocuticle and a-layer in hair fiber cuticle cells, while cornified envelope proteins were absent.

This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.

This study reported that applying natural or artificial folliculoid compounds to mouse skin caused estrous-like changes in internal sex organs, but did not lead to cancerous skin changes.

This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.

This study examined the complex morphology of the cornified claw sheath in domesticated cats, uncovering structures and growth patterns that help maintain sharp claw tips essential for climbing and prey capture.

This study developed new label-free imaging methods to analyze human hair, identifying distinct chemical environments within cuticle layers and changes in hair structure caused by depilatories, while showing that the treatments tested did not significantly affect skin cell differentiation or proliferation.

This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.

This study found that Fos protein expression is closely linked to epithelial cell differentiation, particularly during cornification and cell death, with overexpression observed in keratinization-blocked mutant epidermis.

This review discusses the role of epidermal differentiation complex genes and epigenetic mechanisms in skin development and certain diseases, emphasizing their potential for improving drug development and delivery systems but provides no new experimental results.

This study explains how the development of keratin-associated proteins in embryonic epidermis is crucial for forming protective barriers in vertebrates, enabling them to adapt to terrestrial environments.

This study developed a rapid, cost-effective three-dimensional skin equivalent model using human dermal fibroblasts, collagen, and hair follicles, which closely resembles natural human skin and can be used for autologous transplantation.

This study found that new rabbit antisera against recombinant mouse involucrin effectively marked keratinocyte differentiation, with comparable expression patterns to human involucrin.

This study demonstrates that overexpression of K16 in transgenic mice disrupts normal keratinization, leading to hyperkeratosis, acanthosis, and alterations in the skin's epithelial cells.

This case report details an 80-year-old woman with circle hair potentially linked to acquired ichthyosis from multiple myeloma, where a prescribed topical treatment led to clinical improvement.

This study found that cortisol and corticosterone led to thinning of the epidermis and hair follicle regression in fetal mouse skin, while testosterone promoted differentiation and sebaceous gland development.

This study found that a nonsense mutation in the Cst6 gene of mice leads to severe skin and hair abnormalities, suggesting that cystatin M/E is crucial for epidermal function and viability.

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.

This study reported that a skin equivalent model using human outer root sheath cells and fibroblasts showed the formation of structures similar to human dermis and epidermis within two weeks after transplantation into mice.

This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.

This narrative literature review examined how linking embryonic development with non-genetic skin anomalies can improve diagnostic accuracy, guide prenatal counseling, and enrich dermatology education by revealing specific vulnerabilities in skin morphogenesis and supporting advances in regenerative medicine.

The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This study revealed key cellular dynamics and interactions during early embryonic mouse skin development, highlighting complex transitions from precursor states to diverse multilayered structures.